Experimental immune therapy aims to tame severe transplant complication

NCT ID NCT06920199

First seen Sep 30, 2025 · Last updated May 23, 2026 · Updated 23 times

Summary

This early-stage trial tests a new treatment for people with chronic graft-versus-host disease (cGVHD) that hasn't responded to standard steroids. The treatment uses special immune cells (Treg cells) from the original stem cell donor, combined with a low dose of interleukin-2, to try to control the overactive immune response. The main goal is to check safety and find the right dose in 18 adults aged 18-70.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai General Hospital

    RECRUITING

    Shanghai, 200080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.