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New eczema drug TRB-061 enters first human trials

NCT ID NCT06934252

Recruiting now Disease control Sponsor: TRex Bio, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This early-stage trial tests a new drug called TRB-061 in healthy adults and people with moderate-to-severe atopic dermatitis (eczema). The study checks for safety, side effects, and how the drug moves through the body. Participants receive either TRB-061 or a placebo as injections under the skin. The goal is to see if TRB-061 is safe enough to study further for treating eczema.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
TRB-061
What this could lead to
If successful, this could point toward a new treatment option for moderate-to-severe atopic dermatitis, potentially reducing symptoms and flare-ups.
What could go wrong
This is an early Phase 1 trial focused on safety, not effectiveness. The drug may not work in larger studies or could have side effects. Results are years away from any possible use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MODERATE-TO-SEVERE ATOPIC DERMATITIS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Alfred Health

    NOT_YET_RECRUITING

    Melbourne, 3004, Australia

  • CMAX Clinical Research Pty Ltd

    ACTIVE_NOT_RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Clinical Trials New Zealand Ltd

    RECRUITING

    Hamilton, Waikato Region, 3204, New Zealand

  • Cornerstone Centre for Clinical Research

    RECRUITING

    Coorparoo, Queensland, 4151, Australia

  • MCR Christchurch

    RECRUITING

    Christchurch, 8013, New Zealand

  • MCR Palmerston North

    NOT_YET_RECRUITING

    Palmerston North, 4414, New Zealand

  • MCR Sunshine

    NOT_YET_RECRUITING

    Saint Albans, 3021, Australia

  • Medical Research Institute of New Zealand

    RECRUITING

    Newtown, Wellington Region, 6021, New Zealand

  • Momentum Clinical Research Dunedin

    RECRUITING

    Dunedin, Otago, 9016, New Zealand

  • Momentum Clinical Research Kapiti

    RECRUITING

    Waikanae, Wellington Region, 5036, New Zealand

  • Momentum Clinical Research Pukekohe

    RECRUITING

    Pukekohe, Auckland, 2120, New Zealand

  • Pacific Clinical Research Network-Tasman

    RECRUITING

    Nelson, Tasman District, 7011, New Zealand

  • Pacific Clinical Research Network-Wellington

    RECRUITING

    Upper Hutt, Wellington Region, 5018, New Zealand

  • Pacific Clinical Research Network-West Auckland

    RECRUITING

    Auckland, 0600, New Zealand

  • Paratus Clinical Brisbane Pty Ltd

    RECRUITING

    Albion, Brisbane, 4010, Australia

  • Paratus Clinical Research - Canberra Trial Clinic

    RECRUITING

    Belconnen, Australian Capital Territory, 2617, Australia

  • Paratus Clinical Research Central Coast

    RECRUITING

    Kanwal, New South Wales, 2259, Australia

  • Paratus Clinical Research Melbourne

    RECRUITING

    Melbourne, Victoria, 3070, Australia

  • Paratus Clinical Research Western Sydney

    RECRUITING

    Blacktown, New South Wales, 2148, Australia

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