New hope for aggressive breast cancer: targeted drug tested in organ crisis patients
NCT ID NCT07203729
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests whether trastuzumab rezetecan (SHR-A1811) works better than standard chemotherapy for people with HER2-Low breast cancer that has spread and is causing severe organ problems (visceral crisis). About 184 participants will receive either the new drug or a standard chemo every three weeks. The study measures how long the cancer stays under control and how well patients respond.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trastuzumab rezetecan (SHR-A1811)
What this could lead to
If it works, this could offer a more effective treatment option for people with HER2-Low breast cancer that has spread and is causing organ problems.
What could go wrong
This is a Phase 2 trial, so it is still early. The drug may not work better than standard chemotherapy, and side effects could be serious.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cancer Hospital, Chinese Academy of Medical Sciences
RECRUITINGBeijing, Beijing Municipality, 100021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••