Could an old allergy drug shrink enlarged prostates?

NCT ID NCT06689514

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests whether tranilast, a drug currently used for allergies, can help men with moderate to severe enlarged prostate (BPH). The study will include 30 men aged 55-75 with prostate volumes over 40mL and urinary symptoms. Participants will receive standard care plus either a low or high dose of tranilast to see if it safely reduces prostate size and improves symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tranilast

What this could lead to

If it works, this could point toward a new non-surgical treatment for enlarged prostate, reducing symptoms and improving quality of life.

What could go wrong

This is a very early, small trial with only 30 participants. It may not show enough benefit or could have side effects. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai General Hospital

    RECRUITING

    Shanghai, Outside U.S./Canada, 200086, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai General Hospital

    NOT_YET_RECRUITING

    Shanghai, 200086, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••