New hospital policy slashes blood transfusions in major surgeries
NCT ID NCT04803747
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a hospital policy of giving tranexamic acid to adults undergoing major non-cardiac surgery to reduce the need for blood transfusions. Over 8,400 patients took part across multiple hospitals. The goal was to see if this approach safely lowers transfusion rates and blood clot risks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Grace Hospital
Winnipeg, Manitoba, R3J 3M7, Canada
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Health Sciences North Research Institute
Greater Sudbury, Ontario, P3E 5J1, Canada
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Humber River Hospital
Toronto, Ontario, M3M 0B2, Canada
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Hôpital Montfort
Ottawa, Ontario, K1K 0T2, Canada
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Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7, Canada
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London Health Sciences Centre
London, Ontario, N6A 5A5, Canada
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Ottawa Hospital Research Institute- Civic Campus
Ottawa, Ontario, K1Y 4E9, Canada
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Ottawa Hospital Research Institute- General Campus
Ottawa, Ontario, K1H8L6, Canada
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St. Boniface Hospital
Winnipeg, Manitoba, R2H 2A6, Canada
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University of Manitoba- HSC Campus
Winnipeg, Manitoba, R3E 0W2, Canada