New hospital policy cuts blood transfusions in major surgeries

NCT ID NCT04803747

First seen Jan 29, 2026 · Last updated May 23, 2026 · Updated 13 times

Summary

This study tested whether a hospital policy of using a medicine called tranexamic acid could reduce the need for blood transfusions in adults undergoing major non-cardiac surgery. Over 8,000 patients took part across multiple hospitals. The goal was to see if the policy safely lowered transfusion rates and checked for side effects like blood clots.

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Contacts and locations

Locations

  • Grace Hospital

    Winnipeg, Manitoba, R3J 3M7, Canada

  • Health Sciences North Research Institute

    Greater Sudbury, Ontario, P3E 5J1, Canada

  • Humber River Hospital

    Toronto, Ontario, M3M 0B2, Canada

  • Hôpital Montfort

    Ottawa, Ontario, K1K 0T2, Canada

  • Kingston Health Sciences Centre

    Kingston, Ontario, K7L 2V7, Canada

  • London Health Sciences Centre

    London, Ontario, N6A 5A5, Canada

  • Ottawa Hospital Research Institute- Civic Campus

    Ottawa, Ontario, K1Y 4E9, Canada

  • Ottawa Hospital Research Institute- General Campus

    Ottawa, Ontario, K1H8L6, Canada

  • St. Boniface Hospital

    Winnipeg, Manitoba, R2H 2A6, Canada

  • University of Manitoba- HSC Campus

    Winnipeg, Manitoba, R3E 0W2, Canada

Conditions

Explore the condition pages connected to this study.