Could a common clot drug fade stubborn skin darkening?
NCT ID NCT04233749
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This small phase 2 trial is testing whether tranexamic acid, a drug used to reduce bleeding, can lighten dark patches on the skin caused by lichen planus pigmentosus and erythema dyschromicum perstans. Five adults will take the drug twice daily for six months. Researchers will measure changes in pigmentation using special light devices.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid tablets
What this could lead to
If it works, this could offer a new treatment option for stubborn skin darkening conditions that currently have no effective therapy.
What could go wrong
This is a very small early-phase trial with only 5 participants, so results may not apply widely. Tranexamic acid also carries a risk of blood clots.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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New Center One
RECRUITINGDetroit, Michigan, 48202, United States
Contact Email: •••••@•••••