Could a simple drug cut shoulder surgery pain and opioid use?
NCT ID NCT05302986
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether giving tranexamic acid during shoulder surgery reduces pain and the need for morphine afterward. The idea is that the drug might shrink post-surgery bleeding and swelling, which can cause pain. Researchers compared 220 adults who got either the drug or a placebo during their operation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid
What this could lead to
If it works, this could offer a simple way to reduce pain and morphine use after shoulder surgery.
What could go wrong
This is a completed trial, but results are not yet widely confirmed. The effect on pain may be small, and tranexamic acid carries risks like blood clots in some people.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Polyclinique Jean Villar
Bruges, France, 33520, France