Common drug tested to stop bleeding in blood cancer patients

NCT ID NCT03136445

Summary

This study tested whether tranexamic acid, a drug that helps blood clot, could reduce serious bleeding or death in adults with blood cancers who have very low platelet counts from treatment. Over 600 patients were randomly assigned to receive either the drug or a placebo (dummy treatment) for 30 days. The main goal was to see if the drug could lower the risk of bleeding and reduce the need for platelet transfusions.

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Contacts and locations

Locations

  • Alfred Hospital

    Melbourne, Australia

  • Andrew Love Cancer Centre

    Geelong, Australia

  • Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

  • Belfast City Hospital

    Belfast, United Kingdom

  • Bristol Haematology and Oncology Centre

    Bristol, United Kingdom

  • Canberra Hospital

    Canberra, Australia

  • Churchill Hospital

    Oxford, United Kingdom

  • Derriford Hospital

    Plymouth, United Kingdom

  • Freeman Hospital

    Newcastle, United Kingdom

  • Heartlands Hospital

    Birmingham, United Kingdom

  • King's College Hospital

    London, United Kingdom

  • Lincoln County Hospital

    Lincoln, United Kingdom

  • Monash Health

    Melbourne, Australia

  • Queen Elizabeth Hospital

    Birmingham, United Kingdom

  • Royal Adelaide Hospital

    Adelaide, Australia

  • Royal Brisbane

    Brisbane, Australia

  • Royal Devon and Exeter Hospital

    Exeter, United Kingdom

  • Royal North Shore Hospital

    St Leonards, Australia

  • Royal United Hospital

    Bath, United Kingdom

  • Salisbury District Hospital

    Salisbury, United Kingdom

  • St James's Hospital

    Leeds, United Kingdom

  • St Vincent's Hospital

    Melbourne, Australia

  • St Vincent's Hospital

    Sydney, Australia

  • University College London Hospitals

    London, United Kingdom

  • University Hospital Coventry

    Coventry, United Kingdom

  • Victorian Comprehensive Cancer Centre

    Melbourne, Australia

  • Westmead Hospital

    Westmead, Australia

Conditions

Explore the condition pages connected to this study.