Blood cancer bleeding breakthrough? drug shows promise in major trial

NCT ID NCT03136445

First seen Oct 31, 2025 · Last updated May 05, 2026 · Updated 23 times

Summary

This study tested whether a drug called tranexamic acid can lower the risk of serious bleeding or death in people with blood cancers who have very low platelet counts. Over 600 adults receiving chemotherapy or a stem cell transplant were given either the drug or a placebo. The goal was to see if the drug could reduce the need for platelet transfusions and improve safety.

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Contacts and locations

Locations

  • Alfred Hospital

    Melbourne, Australia

  • Andrew Love Cancer Centre

    Geelong, Australia

  • Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

  • Belfast City Hospital

    Belfast, United Kingdom

  • Bristol Haematology and Oncology Centre

    Bristol, United Kingdom

  • Canberra Hospital

    Canberra, Australia

  • Churchill Hospital

    Oxford, United Kingdom

  • Derriford Hospital

    Plymouth, United Kingdom

  • Freeman Hospital

    Newcastle, United Kingdom

  • Heartlands Hospital

    Birmingham, United Kingdom

  • King's College Hospital

    London, United Kingdom

  • Lincoln County Hospital

    Lincoln, United Kingdom

  • Monash Health

    Melbourne, Australia

  • Queen Elizabeth Hospital

    Birmingham, United Kingdom

  • Royal Adelaide Hospital

    Adelaide, Australia

  • Royal Brisbane

    Brisbane, Australia

  • Royal Devon and Exeter Hospital

    Exeter, United Kingdom

  • Royal North Shore Hospital

    St Leonards, Australia

  • Royal United Hospital

    Bath, United Kingdom

  • Salisbury District Hospital

    Salisbury, United Kingdom

  • St James's Hospital

    Leeds, United Kingdom

  • St Vincent's Hospital

    Melbourne, Australia

  • St Vincent's Hospital

    Sydney, Australia

  • University College London Hospitals

    London, United Kingdom

  • University Hospital Coventry

    Coventry, United Kingdom

  • Victorian Comprehensive Cancer Centre

    Melbourne, Australia

  • Westmead Hospital

    Westmead, Australia

Conditions

Explore the condition pages connected to this study.