New shot could tame severe eczema in kids as young as 6 months

NCT ID NCT06311682

Recruiting now Disease control Sponsor: LEO Pharma Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study tests whether a drug called tralokinumab, given as a shot along with steroid cream, can safely control moderate-to-severe eczema in children aged 6 months to under 12 years. About 195 participants will receive either the drug or a placebo for 16 weeks, then all will get the drug. The trial lasts up to 4 years and tracks skin clearance and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tralokinumab (a biologic drug given as a shot) plus topical corticosteroids (steroid cream)
What this could lead to: If it works, this could provide a new treatment option for young children and infants with hard-to-control eczema, potentially reducing itch and skin flares.
What could go wrong: This is an early-phase trial in a small group, so results may not apply to all children. The drug requires regular injections and may cause side effects like injection reactions or infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Leo Pharma Investigational site
RECRUITING

Birmingham, Alabama, 35209, United States
Leo Pharma Investigational site
RECRUITING

North Little Rock, Arkansas, 72117, United States
Leo Pharma Investigational site
RECRUITING

Palo Alto, California, 94304, United States
Leo Pharma Investigational site
RECRUITING

Sacramento, California, 95816, United States
Leo Pharma Investigational site
WITHDRAWN

San Diego, California, 92108, United States
Leo Pharma Investigational site
RECRUITING

San Diego, California, 92123, United States
Leo Pharma Investigational site
RECRUITING

Jacksonville, Florida, 32256, United States
Leo Pharma Investigational site
RECRUITING

Miami, Florida, 33156, United States
Leo Pharma Investigational site
RECRUITING

Tampa, Florida, 33613, United States
Leo Pharma Investigational site
RECRUITING

Macon, Georgia, 31217, United States
Leo Pharma Investigational site
RECRUITING

Waterford, Michigan, 48328, United States
Leo Pharma Investigational site
RECRUITING

Tulsa, Oklahoma, 74136, United States
Leo Pharma Investigational site
RECRUITING

Portland, Oregon, 97239, United States
Leo Pharma Investigational site
RECRUITING

Charleston, South Carolina, 27420, United States
Leo Pharma Investigational site
RECRUITING

Norfolk, Virginia, 23502, United States
Leo Pharma Investigational site
WITHDRAWN

Brussels, 1020, Belgium
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Ghent, 9000, Belgium
Leo Pharma Investigational site
WITHDRAWN

Leuven, 3000, Belgium
Leo Pharma Investigational site
WITHDRAWN

Liège, 4000, Belgium
Leo Pharma Investigational site
RECRUITING

Burlington, L7L 6W6, Canada
Leo Pharma Investigational site
WITHDRAWN

Calgary, Calgary, Canada
Leo Pharma Investigational site
RECRUITING

Calgary, T2J 7E1, Canada
Leo Pharma Investigational site
RECRUITING

Edmonton, T5J 3S9, Canada
Leo Pharma Investigational site
RECRUITING

Edmonton, T6G 1C3, Canada
Leo Pharma Investigational site
RECRUITING

Hamilton, L8S 1G5, Canada
Leo Pharma Investigational site
RECRUITING

Niagara Falls, L2H 1H5, Canada
Leo Pharma Investigational site
RECRUITING

Saskatoon, S7K 2C1, Canada
Leo Pharma Investigational site
RECRUITING

Windsor, N8X2G1, Canada
Leo Pharma Investigational site
RECRUITING

Winnipeg, R3M 3Z4, Canada
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Rijeka, 51000, Croatia
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Zagreb, 10000, Croatia
Leo Pharma Investigational site
WITHDRAWN

Zagreb, 10000, Croatia
Leo Pharma Investigational site
WITHDRAWN

Buxtehude, 21614, Germany
Leo Pharma Investigational site
WITHDRAWN

Dresden, 01307, Germany
Leo Pharma Investigational site
WITHDRAWN

Mainz, 55131, Germany
Leo Pharma Investigational site
WITHDRAWN

Osnabrück, 49074, Germany
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Tübingen, 72076, Germany
Leo Pharma Investigational site
WITHDRAWN

Wuppertal, 42283, Germany
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Cork, T12 DFK4, Ireland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Crumlin, D12N512, Ireland
Leo Pharma Investigational site
WITHDRAWN

Ancona, 60126, Italy
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Brescia, 25123, Italy
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Padova, 35128, Italy
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Roma, 00168, Italy
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Rome, 00165, Italy
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Utrecht, 3584 CW, Netherlands
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Gdansk, 80-546, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Krakow, 30-002, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Lodz, 90-436, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Ostrowiec Świętokrzyski, 27-400, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Rzeszów, 35-055, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Tarnów, 33-100, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Warsaw, 02-953, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Warsaw, 02-962, Poland
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Brasov, 500091, Romania
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Iași, 700259, Romania
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Ansan-si, 15355, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Gwangju, 61453, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Seoul, 02447, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Seoul, 03722, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Seoul, 05030, South Korea
Leo Pharma Investigational site
WITHDRAWN

Seoul, 06273, South Korea
Leo Pharma Investigational site
WITHDRAWN

Seoul, 06591, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Seoul, 139-711, South Korea
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Alicante, 03010, Spain
Leo Pharma Investigational site
WITHDRAWN

Madrid, 28046, Spain
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Valencia, 46014, Spain
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Lincoln, LN2 5QY, United Kingdom
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

London, WC1N 3JH, United Kingdom
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Sheffield, S10 2TH, United Kingdom
Leo Pharma Investigational site
ACTIVE_NOT_RECRUITING

Southampton, SO16 6YD, United Kingdom

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