Can a pill tame diabetes and obesity together?
NCT ID NCT07747857
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial is testing an experimental oral medication called TQF3250 in people with type 2 diabetes who are also overweight or obese. The drug is designed to mimic a natural hormone that helps control blood sugar and appetite. The study aims to see if the drug is safe, tolerable, and shows early signs of helping with blood sugar control and weight loss. Participants will receive either the drug or a placebo, and the trial will compare different doses to find the most promising one.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TQF3250 capsules, an oral glucagon-like peptide-1 (GLP-1) receptor agonist
- What this could lead to
- If successful, this could lead to a convenient oral treatment option for managing type 2 diabetes and weight, potentially improving blood sugar control and aiding weight loss.
- What could go wrong
- This is an early-phase trial with a small number of participants, so the safety and effectiveness are not yet established. The drug may not work as hoped or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, 646099, China
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Central Hospital Affiliated to Shandong First Medical University
Jinan, Shandong, 250013, China
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Fuzhou University Affiliated Provincial Hospital
Fuzhou, Fujian, 350001, China
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Hebei Petro China Central Hosptial
Langfang, Hebei, 065000, China
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Luoyang First People's Hospital
Luoyang, Henan, 471000, China
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Nanjing Drum Tower Hospital
Nanjing, Jiangsu, 210008, China
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Shanghai Tenth People's Hospital
Shanghai, Shanghai Municipality, 200072, China
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Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, 510000, China
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The First People's Hospital of Xiaoshan Hangzhou
Hangzhou, Zhejiang, 311201, China
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The Third Hospital of Changsha
Changsha, Hunan, 410015, China
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Yichang Central People's Hospital
Yichang, Hubei, 443003, China
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Zhongnan Hospital of Wuhan University
Wuhan, Hubei, 430000, China