New hope for breast cancer patients whose tumors resisted standard therapy

NCT ID NCT06702618

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tests a new drug (TQB3616) combined with hormone therapy for people with a common type of breast cancer (HR-positive, HER2-negative) that has returned or spread and no longer responds to a standard class of drugs called CDK4/6 inhibitors. The trial enrolls 33 adults aged 18-75 who have already tried a CDK4/6 inhibitor. The main goal is to see if the tumor shrinks or disappears, and researchers also track how long the benefit lasts.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer Hospital of Shandong First Medical University(Shandong Cancer Institute, Shandong Cancer Hospital)

    Jinan, Shandong, 250117, China

  • Hai'an People's Hospital

    Nantong, Jiangsu, 226600, China

  • Harbin Medical University Cancer Hostipal

    Harbin, Heilongjiang, 150000, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410010, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, 529000, China

  • Jiangsu Provincial People's Hospital

    Nanjing, Jiangsu, 210003, China

  • Liaoning Cancer Hospital

    Shenyang, Liaoning, 110000, China

  • Luohe Central Hospital

    Luohe, Henan, 462000, China

  • The Affiliated Hospital of Southwest Medical University

    Luzhou, Sichuan, 646000, China

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    Xi’an, Shanxi, 710061, China

  • The First Affilliated Hospital of Bengbu Medical University

    Bengbu, Anhui, 233000, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, 300202, China

  • Xingtai People's Hospital

    Xingtai, Hebei, 54000, China

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