New hope for resistant breast cancer: experimental pill shows promise in early trial

NCT ID NCT06702618

First seen Apr 11, 2026 · Last updated May 21, 2026 · Updated 2 times

Summary

This phase 2 trial tests a new oral drug (TQB3616) combined with hormone therapy for people with a common type of breast cancer (HR-positive, HER2-negative) that has stopped responding to standard CDK4/6 inhibitor pills. The study enrolls 33 adults whose cancer has returned or spread. The main goal is to see how many patients' tumors shrink or disappear, while also tracking how long the benefit lasts and any side effects.

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Contacts and locations

Locations

  • Cancer Hospital of Shandong First Medical University(Shandong Cancer Institute, Shandong Cancer Hospital)

    Jinan, Shandong, 250117, China

  • Hai'an People's Hospital

    Nantong, Jiangsu, 226600, China

  • Harbin Medical University Cancer Hostipal

    Harbin, Heilongjiang, 150000, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410010, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, 529000, China

  • Jiangsu Provincial People's Hospital

    Nanjing, Jiangsu, 210003, China

  • Liaoning Cancer Hospital

    Shenyang, Liaoning, 110000, China

  • Luohe Central Hospital

    Luohe, Henan, 462000, China

  • The Affiliated Hospital of Southwest Medical University

    Luzhou, Sichuan, 646000, China

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    Xi’an, Shanxi, 710061, China

  • The First Affilliated Hospital of Bengbu Medical University

    Bengbu, Anhui, 233000, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, 300202, China

  • Xingtai People's Hospital

    Xingtai, Hebei, 54000, China

Conditions

Explore the condition pages connected to this study.