New drug tested for tough transplant complication

NCT ID NCT04944043

Summary

This study is testing an oral drug called TQ05105 for adults with a serious complication called chronic graft-versus-host disease (cGVHD) that has not responded well to standard steroid treatment. The trial aims to find a safe and effective dose and see if the drug can help control the disease and reduce symptoms. It involves 45 participants who have had a stem cell transplant and are struggling with moderate to severe cGVHD.

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Contacts and locations

Locations

  • Guangzhou First People's Hospital

    Guangzhou, Guangdong, 511457, China

  • Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

    Tianjin, Tianjin Municipality, 300020, China

  • Nanfang Hospital of Southern Medical University

    Guangzhou, Guangdong, 510515, China

  • The First Affiliated Hospital of Guangxi Medical University

    Nanning, Guangxi, 530021, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215006, China

  • The First Affiliated Hospital of USTC (Anhui Provincial Hospital)

    Hefei, Anhui, 230001, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Hanzhou, Zhejiang, 310000, China

  • The Second Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 050000, China

  • Tongji Hospital Tongji Medical College of HUST

    Wuhan, Hubei, 430030, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Zhujiang Hospital of Southern Medical University

    Guangzhou, Guangdong, 510280, China

Conditions

Explore the condition pages connected to this study.