Double-Drug attack on chemo side effect: can two platelet boosters work better than one?

NCT ID NCT06769685

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a combination of two drugs—rhTPO and hetrombopag—to raise platelet counts in 100 cancer patients whose platelets dropped due to chemotherapy. Patients are split into two groups based on how low their platelets are, and both groups receive the same drug combo until their platelets reach a safe level. The main goal is to see how quickly platelets recover, with a focus on reducing bleeding and treatment delays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
recombinant human thrombopoietin (rhTPO) and hetrombopag
What this could lead to
If successful, this could offer a faster, more effective way to raise platelet counts in cancer patients whose platelets drop due to chemotherapy, reducing bleeding risks and treatment delays.
What could go wrong
This is a small, early-phase (Phase 2) single-center study with only 100 participants. It is not randomized or blinded, so results may not apply broadly. Side effects from the drug combination are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jinhua Central Hospital

    Jinhua, Zhejiang, 321000, China

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