Knee surgery tourniquet mystery: why some Patients' hearts slow down when the cuff is released
NCT ID NCT07002086
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 22 patients aged 65-90 who had total knee replacement surgery. Researchers wanted to understand why some patients experience a sudden drop in heart rate and blood pressure when the tourniquet (a tight cuff that stops blood flow) is released at the end of surgery. They measured blood clotting factors and other markers before and after the tourniquet was opened. The goal was to learn how to prevent these dangerous changes in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors prevent dangerous drops in heart rate and blood pressure when the tourniquet is released during knee replacement surgery.
- What could go wrong
- This is a very small, completed observational study with only 22 patients. It does not test a new treatment, so it cannot directly lead to a cure or therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Diyarbakır, 21070, Turkey (Türkiye)