Immunotherapy drug shows promise for Hard-to-Treat cancers with specific gene changes

NCT ID NCT03810339

First seen Apr 23, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tests a drug called toripalimab, which helps the immune system fight cancer. It is for adults with advanced solid tumors that have specific gene changes (POLE or POLD-1) but not high microsatellite instability. The goal is to see if the drug can shrink tumors and control the cancer for as long as possible.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer center of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Guizhou Medical University

    RECRUITING

    Guiyang, Guizhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.