Promising cream for rare skin condition falls short in early trial
NCT ID NCT03363763
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a sirolimus cream (0.2% and 0.4%) applied daily for 12 weeks to treat facial angiofibromas in children aged 2-21 with tuberous sclerosis complex. The goal was to see if the cream could safely reduce the size and redness of these skin growths. The trial was terminated early, so results are limited and no clear conclusions can be drawn.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Clinical Research Organization, Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30329, United States
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Children's Hospital of Fudan University
Shanghai, 201102, China
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Children's Hospital of Los Angeles, Division of Neurology
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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LeBonheur Children's Hospital
Memphis, Tennessee, 38103, United States
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Translational Genomics Research
Phoenix, Arizona, 85004, United States