Numbing spray may skew voice tests in reflux patients

NCT ID NCT07696429

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study investigates whether a topical numbing spray (lidocaine) affects voice recordings during high-speed laryngoscopy in adults with laryngopharyngeal reflux (LPR). Participants receive either lidocaine spray or a placebo on two separate days, and researchers compare voice parameters like vocal fold movement and sound quality. The goal is to determine if anesthesia alters the results, which could improve how voice exams are interpreted in LPR patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Lidocaine 10% Spray
What this could lead to
If it works, this could help doctors understand whether numbing spray alters voice measurements, leading to more accurate laryngoscopy results.
What could go wrong
This is a small, early-stage study focused on measurement, not treatment. Results may not apply to other populations or voice conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Laryngopharyngeal Reflux

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Centre Zagreb (KBC Zagreb), Department of ORL Head and Neck Surgery

    Zagreb, 10000, Croatia

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