New No-Surgery fix for heartburn tested in 500 patients

NCT ID NCT07395219

First seen Feb 10, 2026 · Last updated May 22, 2026 · Updated 15 times

Summary

This study tracks 500 adults with acid reflux or throat reflux who receive a procedure called TIF 2.0, which tightens the valve between the stomach and esophagus without any cuts. Researchers will measure changes in reflux symptoms and use of acid-reducing medications over time. The goal is to see if this minimally invasive approach is safe and helps control the disease long-term.

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Contacts and locations

Locations

  • Cleveland Clinic

    Abu Dhabi, United Arab Emirates

  • Cleveland Clinic London

    London, United Kingdom

  • Department of General Surgery, Medical University of Vienna

    Vienna, Austria

  • Gemelli Isola

    Rome, Italy

  • Intesto

    Bern, Switzerland

  • Memorial bahçelievler hospital

    Istanbul, Turkey (Türkiye)

  • University Hospital for Digestive Surgery

    Belgrade, Serbia

Conditions

Explore the condition pages connected to this study.