Blood transfusion study aims to boost survival and brain health in tiniest babies

NCT ID NCT01702805

First seen Nov 15, 2025 · Last updated May 03, 2026 · Updated 20 times

Summary

This study looked at whether giving more red blood cell transfusions (liberal strategy) to extremely low birth weight infants (under 2.2 pounds) helps them survive and develop better than a more restrictive approach. Over 1,800 babies from NICUs across the U.S. took part. The main goal was to see if the liberal strategy reduced death or brain development problems by age 2.

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Contacts and locations

Locations

  • Brown University, Women & Infants Hospital of Rhode Island

    Providence, Rhode Island, 02905, United States

  • Case Western Reserve University, Rainbow Babies and Children's Hospital

    Cleveland, Ohio, 44106, United States

  • Children's Mercy Hospital

    Kansas City, Missouri, 64108, United States

  • Cincinnati Children's Medical Center

    Cincinnati, Ohio, 45267, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Emory University

    Atlanta, Georgia, 30303, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • RTI International

    Durham, North Carolina, 27705, United States

  • Research Institute at Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Stanford University

    Palo Alto, California, 94304, United States

  • Univeristy of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of California - Los Angeles

    Los Angeles, California, 90025, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of New Mexico

    Albuquerque, New Mexico, 87131, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

  • University of Texas Southwestern Medical Center at Dallas

    Dallas, Texas, 75235, United States

  • University of Utah

    Salt Lake City, Utah, 84108, United States

  • Wayne State University

    Detroit, Michigan, 48201, United States

Conditions

Explore the condition pages connected to this study.