Can your own muscle cells fix swallowing? early trial begins
NCT ID NCT02838316
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether injecting a person's own muscle cells into the tongue can safely improve swallowing problems caused by cancer treatment. The study involves 18 adults who had surgery, chemo, or radiation for oropharyngeal cancer at least two years ago. Researchers will monitor for side effects over 12 months and check if swallowing function gets better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Autologous muscle derived stem cells (AMDC-GIR)
What this could lead to
If successful, this could point toward a new treatment to improve swallowing in people with tongue weakness after cancer therapy.
What could go wrong
This is a very early Phase 1 safety trial with only 18 people. It is not designed to prove effectiveness, and the treatment may not improve swallowing or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UC Davis Medical Center, Department of Otolaryngology, Head and Neck Surgery
Sacramento, California, 95817, United States