Can we predict who can safely lower Anti-Rejection drugs after hand or face transplants?
NCT ID NCT02055521
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked for immune tolerance markers in 18 hand and face transplant recipients (transplanted at least one year prior). Researchers analyzed blood and skin biopsies to find a 'tolerance signature' that might identify patients who could safely reduce their lifelong anti-rejection medication. The goal is to minimize drug side effects while preventing graft rejection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors identify which transplant recipients can safely lower their anti-rejection drugs, reducing side effects.
What could go wrong
This is a small, observational study (18 people) looking for biological markers, not testing a new treatment. The markers may not reliably predict tolerance in hand or face transplants.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Hospices Civils de Lyon
Lyon, 69003, France