Swedish registry study checks how tofacitinib works in ulcerative colitis patients

NCT ID NCT04338204

First seen Dec 08, 2025 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This completed study in Sweden observed 102 people with ulcerative colitis who were prescribed tofacitinib as part of their normal care. Researchers used a national registry to track how well the drug controlled disease activity and whether patients stayed on treatment. The goal was to see how tofacitinib performs in real-world settings, not in a controlled experiment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Danderyds Hospital

    Stockholm, 18257, Sweden

  • Daniel Molin

    Kristianstad, 29185, Sweden

  • Ersta Sjukhus, Medicinkliniken, Fjällgatan 44

    Stockholm, 11691, Sweden

  • Gävle Hospital

    Gävle, 80324, Sweden

  • Karolinska Universitetssjukhuset i Solna, Eugeniavägen 3, B4-09,

    Stockholm, 17176, Sweden

  • Mag-Tarmmedicinska kliniken, Universitetssjukhuset i Linköping

    Linköping, 58185, Sweden

  • Medicinkliniken, Länssjukhuset Ryhov, Sjukhusgatan

    Jönköping, 55185, Sweden

  • Medicinkliniken, Södra Älvsborgs Sjukhus Borås, Brämhultsvägen 53

    Borås, Sweden

  • Medicinkliniken, Umeås Universitetssjukhus

    Umeå, 50985, Sweden

  • Medicinmottagning 4, Medicinska Kliniken, Universitetssjukhuset Örebro

    Örebro, 70185, Sweden

  • Medicinmottagningen gastroenterologi, Västmanlands sjukhus

    Västerås, 72189, Sweden

  • Region skåne, Skånes Universitetssjukhus

    Malmö, 20501, Sweden

  • SU/Sahlgrenska, Gastroenterologi & Hepatologi

    Gothenburg, Göteborg, Sweden

  • Shiprock Consulting AB,

    Lidingö, Sweden

  • Specialmedicin, Akademiska Sjukhuset, Sjukhusvägen ing 40

    Uppsala, 75185, Sweden

  • Stockholm Gastro Center

    Stockholm, 11486, Sweden

  • Ulf Eriksson

    Alingsås, SE-441 33, Sweden

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tofacitinib

What this could lead to

If successful, this study could show how well tofacitinib works in everyday care for ulcerative colitis, helping doctors make better treatment decisions.

What could go wrong

This is an observational study, not a controlled trial, so results may be influenced by factors like patient selection. It cannot prove cause and effect.

Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.