New combo therapy could ease painful mouth condition

NCT ID NCT07131813

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the drug tofacitinib to standard steroid ointment can better control oral lichen planus, a chronic inflammatory mouth condition. About 60 adults with moderate to severe disease will receive either tofacitinib pills or placebo alongside their usual steroid treatment for 12 weeks. The goal is to see if the combination reduces disease severity and pain more effectively while potentially lowering steroid-related side effects.

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Conditions

The condition(s) this trial relates to.

lichen planus, oral

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AIIMS, Bhubaneswar

    RECRUITING

    Bhubaneswar, Odisha, 751019, India

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact