New drug combo could ease painful mouth condition

NCT ID NCT07131813

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests whether adding the drug tofacitinib to standard steroid treatment helps people with oral lichen planus, a chronic inflammatory mouth condition. About 60 adults with moderate to severe symptoms will receive either tofacitinib or a placebo alongside their usual steroid ointment for 12 weeks. The goal is to see if the combination reduces disease severity and pain better than steroids alone, while potentially lowering steroid side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AIIMS, Bhubaneswar

    RECRUITING

    Bhubaneswar, Odisha, 751019, India

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.