Gene clues could personalize Crohn's treatment
NCT ID NCT07263464
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 818 people with Crohn's disease to see if variations in the TNFSF4 gene are linked to the disease and how well patients respond to the drug ustekinumab. Researchers analyzed blood samples to find genetic patterns. The goal is to better understand why some patients benefit more from treatment than others.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict which Crohn's patients will respond best to ustekinumab, leading to more personalized treatment.
What could go wrong
This is an observational study, not a treatment trial. It looks at genetic links, so it won't directly test a new therapy. Results may not change practice immediately.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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the Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China