New triple therapy aims to wipe out aggressive breast cancer before surgery

NCT ID NCT05491226

First seen Apr 24, 2026 · Last updated May 03, 2026 · Updated 1 time

Summary

This study tests whether adding a drug called axatilimab (which targets immune cells) and radiation to standard immunotherapy (pembrolizumab) can completely eliminate triple-negative breast cancer before surgery. About 35 women with high-risk, early-stage disease will receive this combination. The main goal is to see if no cancer remains in the breast or lymph nodes at the time of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.