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Could a single burst of magnetic pulses lift depression in autism?

NCT ID NCT06142955

Recruiting now Symptom relief Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study explores whether a single session of transcranial magnetic stimulation (TMS) can reduce depression symptoms in adults with autism spectrum disorder. Researchers will use brain wave recordings (EEG) and eye-tracking to see how the brain responds to sad faces before and after the stimulation. The goal is to gather early clues about whether TMS might be a useful treatment for depression in this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a single session of intermittent Theta Burst Stimulation (iTBS) using the MAGSTIM Rapid2 TMS system
What this could lead to
If it works, this could point toward a non-invasive, drug-free treatment for depression in people with autism spectrum disorder.
What could go wrong
This is a small, early-phase study testing only one session, so it cannot show lasting benefits. The results may not apply to everyone with autism.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale Psychiatric Hospital

    RECRUITING

    New Haven, Connecticut, 06520, United States

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