Sound waves to zap high blood pressure: new device trial begins
NCT ID NCT05372679
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a device called TIVUS that uses ultrasound to calm overactive nerves in the kidneys, which can drive high blood pressure. It includes 25 adults with uncontrolled stage 2 hypertension who have not responded well to medication. The main goal is to see if the procedure safely lowers blood pressure over three months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Therapeutic Intra-Vascular Ultrasound (TIVUS) system for renal denervation
- What this could lead to
- If it works, this could offer a new, drug-free way to control high blood pressure for people who don't respond well to medication.
- What could go wrong
- This is a small, early-stage study with only 25 participants and no comparison group, so results may not apply to everyone. The procedure also carries risks like kidney injury or artery damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Arkansas Heart Hospital
Little Rock, Arkansas, 72211, United States
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Bridgeport Hospital
Bridgeport, Connecticut, 06610, United States
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Cardiology P.C.
Birmingham, Alabama, 35211, United States
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Columbia University/NYPH
New York, New York, 10032, United States
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Medical University South Carolina
Charleston, South Carolina, 29425, United States
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Minneapolis Heart Institution Foundation
Minneapolis, Minnesota, 55407, United States
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NC Heart and Vascular Research, LLC
Raleigh, North Carolina, 27607, United States
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Prairie Education and Research Cooperative
Springfield, Illinois, 62701, United States
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ST Bernards Medical Center
Jonesboro, Arkansas, 72401, United States