New cancer drug shows promise in advanced tumors

NCT ID NCT03485209

Ongoing Disease control Sponsor: Seagen, a wholly owned subsidiary of Pfizer Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an experimental drug called tisotumab vedotin, given alone or with other cancer drugs, can help control advanced solid tumors. It enrolled 352 people with advanced colorectal, lung, pancreatic, or head and neck cancers that had stopped responding to standard treatments. The main goal is to see if the treatment shrinks tumors and to understand its side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

ALTHAIA, Xarxa Assistencial Universitaria de Manresa.

Manresa, Barcelona, 08243, Spain
AOU Università degli studi della Campania Luigi Vanvitelli, Policlinico di Napoli

Naples, 80131, Italy
Atrium Health Wake Forest Baptist Health

Winston-Salem, North Carolina, 27157, United States
Atrium Health Wake forest Baptist

Winston-Salem, North Carolina, 27157, United States
Azienda Ospedaliera Universitaria - Universita della Campania Luigi Vanvitelli

Naples, 80131, Italy
Barnes-Jewish Hospital

St Louis, Missouri, 63110, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
C/O Thomas Ferenez.RPh,BCOP,Smilow Cancer Hospital at Yale-New Haven

New Haven, Connecticut, 06511, United States
CEPCM/CHU Timone, Batiment 3 -1er etage

Marseille, 13005, France
CHRU de Besançon- Hopital Jean Minjoz

Besançon, Doubs, 25030, France
Cancer Care & Hematology - Fort Collins

Fort Collins, Colorado, 80528, United States
Cancer Care & Hematology - Greeley

Greeley, Colorado, 80634, United States
Cancer Care & Hematology - Loveland

Loveland, Colorado, 80538, United States
Cancer Center IDS Pharmacy

Charlottesville, Virginia, 22903, United States
Clinical Research Facility - Clinical Research Facility

London, London, CITY of, SE1 9RT, United Kingdom
Community Health Network, Inc.

Indianapolis, Indiana, 46219, United States
Community Health Network, Inc.

Indianapolis, Indiana, 46227, United States
Community Health Network, Inc.

Indianapolis, Indiana, 46250, United States
Community Health Network, Inc.

Indianapolis, Indiana, 46256, United States
Cross Cancer Institute

Edmonton, Alberta, T6G 1Z2, Canada
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Duke Cancer Center

Durham, North Carolina, 27710, United States
Duke Raleigh Hospital

Raleigh, North Carolina, 27609, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Eye Center of Northern Colorado

Fort Collins, Colorado, 80525, United States
Eye Center of Northern Colorado

Fort Collins, Colorado, 80528, United States
Family Focus Eye Care - Gainesville

Gainesville, Florida, 32605, United States
Family Focus Eye Care - Lake City

Lake City, Florida, 32025, United States
Farmacia Oncologica c/o Ospedale S.Maria delle Croci-AUSL Romagna

Ravenna, 48121, Italy
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca

Barcelona, 08035, Spain
Gustave Roussy

Villejuif, 94805, France
Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital

London, London, CITY of, Se1 9Rt, United Kingdom
Guys and St Thomas Hospital

London, Other, SE1 9RT, United Kingdom
Hopital prive du Confluent S.A.S.

Nantes, 44277, France
Hospital Quiron Salud Barcelona Plaza

Barcelona, 08023, Spain
Hospital Quironsalud Barcelona Instituto Oncologico Baselga

Barcelona, Catalonia, 08023, Spain
Hospital Universitario Dexeus - Grupo Quirónsalud

Barcelona, 08028, Spain
Hospital Universitario Ramon y Cajal

Madrid, 28034, Spain
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Hôpital Foch

Suresnes, 92150, France
Hôpital Foch Pharmacie - Essais Cliniques

Suresnes, 92150, France
IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori- IRST S.r.l

Meldola (Fc), Emilia-Romagna, 47014, Italy
IRST IRCCS - Farmacia Oncologica

Meldola (FC), Forli-cesena, 47014, Italy
Ingalls Memorial Hospital

Harvey, Illinois, 60426, United States
Institut Catala D 'Oncologia-Hospital Germans Trias I Pujol,Servicio de Oncologia Medica

Barcelona, Badalona, 08916, Spain
Institut Catala d'Oncologia (ICO BADALONA)

Barcelona, 08908, Spain
Investigational Chemotherapy Service

Durham, North Carolina, 27710, United States
Investigational Drug Service, Emory University Clinic

Atlanta, Georgia, 30322, United States
Istituto Europeo di Oncologia

Milan, MI, 20141, Italy
Joe Arrington Cancer Research and Treatment Center

Lubbock, Texas, 79410, United States
John Hopkins Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland, 21231, United States
John Hopkins Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland, 21287, United States
Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Karmanos Cancer Institute Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
L'hôpital Privé du Confluent - Pharmacie

Nantes, 44277, France
LBM UNIBIO Jean Herve Lebras

Tain-l'Hermitage, 26600, France
Laboratoire Cerballiance Portes Les Valence

Portes-lès-Valence, 26800, France
Laboratoire Oriade Noviale Medipole

Bourgoin, 38300, France
Laboratoire Oriade Noviale Tixier

Bourgoin, 38300, France
Laboratoire Trevoux-Dyomedea Neolab

Trévoux, 01600, France
Lbmms Du Chu de Lyon

Lyon, 69424 CEDEX 03, France
MSK Basking Ridge.

Basking Ridge, New Jersey, 07920, United States
MSK Bergen

Montvale, New Jersey, 07645, United States
MSK Commack.

Commack, New York, 11725, United States
MSK Monmouth

Middletown, New Jersey, 07748, United States
MSK Nassau.

Uniondale, New York, 11553, United States
MSK Westchester.

Harrison, New York, 10604, United States
Massachusetts Eye and Ear Infirmary(MEEI)

Boston, Massachusetts, 02114, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Mayo Clinic Rochester

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street).

New York, New York, 10021, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Moffitt Cancer Center McKinley Hospital

Tampa, Florida, 33612, United States
North Carolina Basnight Cancer Hospital Infusion Pharmacy

Chapel Hill, North Carolina, 27514, United States
Northwestern Medical Group

Chicago, Illinois, 60611, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern Medicine Delnor Hospital

Geneva, Illinois, 60134, United States
Northwestern Medicine Kishwaukee Hospital

DeKalb, Illinois, 60115, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Northwestern University

Evanston, Illinois, 60208, United States
Norton Audubon Hospital

Louisville, Kentucky, 40217, United States
Norton Brownsboro Hospital

Louisville, Kentucky, 40241, United States
Norton Cancer Institute Pharmacy

Louisville, Kentucky, 40202, United States
Norton Cancer Institute, Audubon Hospital Campus

Louisville, Kentucky, 40217, United States
Norton Cancer Institute, Brownsboro Hospital Campus

Louisville, Kentucky, 40241, United States
Norton Cancer Institute, Downtown

Louisville, Kentucky, 40202, United States
Norton Hospital

Louisville, Kentucky, 40202, United States
OHSU Center for Health and Healing

Portland, Oregon, 97239, United States
OHSU Center for Health and Healing 2

Portland, Oregon, 97239, United States
OHSU Knight Cancer Institute, Beaverton

Beaverton, Oregon, 97006, United States
OHSU Knight Cancer Institute, East Portland

Portland, Oregon, 97216, United States
OHSU Knight Cancer Institute, Gresham

Gresham, Oregon, 97030, United States
OHSU Knight Cancer Institute, Northwest Portland

Portland, Oregon, 97210, United States
OHSU Knight Cancer Institute, Tualatin

Tualatin, Oregon, 97062, United States
Oncologia Medica, Ospedale Civile S. Maria delle Croci

Ravenna, Emilia-Romagna, 48121, Italy
Oncology Research, HealthPartners Institute

Saint Louis Park, Minnesota, 55426, United States
Ophthalmic Consultants of Boston Inc (OCB)

Boston, Massachusetts, 02114, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Oregon Health and Science University Research Pharmacy Services

Portland, Oregon, 97239, United States
Ospedale Cervesi di Cattolica-AUSL Romagna

Cattolica, RN, 47841, Italy
Ospedale S.Jacopo di Pistoia, AUSL Toscana centro, SST

Pistoia, 51100, Italy
Ospedale Umberto I di Lugo, AUSL della Romagna, SSR Emilia-Romagna

Lugo, 48022, Italy
Ospedale degli Infermi -AUSL Romagna

Rimini, RN, 47923, Italy
PO Ospedale degli Infermi Faenza, AUSL Romagna

Faenza, 48018, Italy
Park Nicollet Frauenshuh Cancer Center

Saint Louis Park, Minnesota, 55426, United States
Pharmacy Stores (CCR5916) - The Royal Marsden

Sutton, Surrey, SM2 5PT, United Kingdom
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Primary Healthcare Associates

Flossmoor, Illinois, 60422, United States
Primary Healthcare Associates

Harvey, Illinois, 60426, United States
Primary Healthcare Associates

Tinley Park, Illinois, 60477, United States
Renovatio Clinical.

The Woodlands, Texas, 77380, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Richard M Schulze Family Foundation Outpatient Center at McKinley Campus

Tampa, Florida, 33612, United States
Royal Marsden Hospital NHS Foundation Trust - HNTU

Sutton, SM2 5PT, United Kingdom
Simlow Cancer Hospitalat Yale-New Haven

New Haven, Connecticut, 06510, United States
Siteman Cancer Center - North County

Florissant, Missouri, 63031, United States
Siteman Cancer Center - South County

St Louis, Missouri, 63129, United States
Siteman Cancer Center - St. Peters

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center - West County

Creve Coeur, Missouri, 63141, United States
Stanford Cancer Center South Bay

San Jose, California, 95124, United States
Synlab Bourgogne Pont de Vaux

Pont-de-Vaux, 01190, France
The Centre Léon Bérard

Lyon, 69373, France
The Emory Clinic

Atlanta, Georgia, 30322, United States
The Eye Care Institute

Louisville, Kentucky, 40206, United States
The Miriam Hospital

Providence, Rhode Island, 02906, United States
The Royal Marsden NHS Foundation Trust (RM).

London, SW3 6JJ, United Kingdom
The Royal Marsden NHS Foundation trust (RM)

Sutton, SM2 5PT, United Kingdom
The University of Chicago Medicine Center for Advanced Care Orland Park

Orland Park, Illinois, 60462, United States
The University of Kansas Cancer Center

Westwood, Kansas, 66205, United States
The University of Kansas Cancer Center ,Investigational Drug Services

Fairway, Kansas, 66205, United States
The University of Kansas Clinical Research Center

Fairway, Kansas, 66205, United States
The University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States
The University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States
U.O. Oncologia

Brescia, Lombardy, 25123, Italy
UC San Diego Health - Rancho Bernardo

San Diego, California, 92127, United States
UC San Diego Medical Center - La Jolla (Jacobs Medical Center / Thornton Pavilion)

La Jolla, California, 92037, United States
UC San Diego Medical Center- Hillcrest

San Diego, California, 92103, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92037, United States
UC San Diego/Moores Cancer Center

La Jolla, California, 92093, United States
UCSD Koman Family Outpatient Pavilion

La Jolla, California, 92037, United States
UCSD Medical Center - Encinitas

Encinitas, California, 92024, United States
UCSD Medical Center - Vista

Vista, California, 92081, United States
UCSD Shiley Eye Institute

La Jolla, California, 92093, United States
UChicago Medicine - River East

Chicago, Illinois, 60611, United States
UChicago Medicine Ingalls Memorial

Harvey, Illinois, 60426, United States
UChicago Medicine at Ingalls - Flossmoor

Flossmoor, Illinois, 60422, United States
UChicago Medicine at Ingalls - Tinley Park

Tinley Park, Illinois, 60477, United States
UF Health Davis Cancer Pavilion and Shands Med Plaza

Gainesville, Florida, 32608, United States
UF Health Shands Cancer Hospital

Gainesville, Florida, 32608, United States
UF Health Shands Hospital

Gainesville, Florida, 32610, United States
UNC Hospitals, The University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27514, United States
UOC Oncologia Medica

Rome, Lazio, 00128, Italy
UVA Health System; Attention: GI Team

Charlottesville, Virginia, 22908, United States
University of California Davis Medical Center

Sacramento, California, 95817, United States
University of California, Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center at Silver Cross Hospital

New Lenox, Illinois, 60451, United States
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
University of Virginia Comprehensive Cancer Center

Charlottesville, Virginia, 22903, United States
University of Virginia Health System

Charlottesville, Virginia, 22908, United States
Vall d'Hebron University Hospital

Barcelona, 08023, Spain
Vincentius-Diakonissen-Kliniken gAG Medizinische Klinik 2

Karlsruhe, 76137, Germany
Vincentius-Diakonissen-Klinken Gag Augenklinik

Karlsruhe, 76135, Germany
Vincentius-Diakonissen-Klinken Gag Radiologisches Institut

Karlsruhe, 76137, Germany
Washington University - Investigational Drug Service Pharmacy

St Louis, Missouri, 63110, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Winship Cancer Institute, Emory University

Atlanta, Georgia, 30322, United States
Yale University

New Haven, Connecticut, 06511, United States
Yale-New Haven Hospital- Yale Cancer Center

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

CARCINOMA, NON-SMALL-CELL LUNG CARCINOMA, SQUAMOUS CELL OF HEAD AND NECK COLORECTAL NEOPLASMS EXOCRINE PANCREATIC CANCER