Drug shrinks tumors before surgery in promising cancer trial

NCT ID NCT05116085

Summary

This study tested whether giving the immunotherapy drug tislelizumab before surgery could help people with early-stage colorectal cancer that has specific genetic features (called MSI-H or dMMR). The goal was to see if the drug could shrink or even eliminate the tumor before it was surgically removed. Researchers measured how much cancer was left after the drug treatment and monitored patients for side effects and long-term outcomes.

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Contacts and locations

Locations

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

  • Liaoning Cancer Hospital and Institute

    Shenyang, Liaoning, 110042, China

  • Shandong Cancer Hospital

    Jinan, Shandong, 250117, China

  • Sun Yat Sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The Affiliated Hospital of Qingdao University Branch South

    Qingdao, Shandong, 266000, China

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, Anhui, 233004, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

Conditions

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