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New combo therapy aims to boost stroke recovery

NCT ID NCT07290751

Recruiting now Disease control Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding the blood thinner tirofiban after standard clot-busting treatment helps people with acute ischemic stroke recover better. About 976 adults whose stroke symptoms don't improve enough within an hour of initial treatment will receive either tirofiban or a placebo for 24 hours. The goal is to see if more patients achieve functional independence at 90 days, while carefully monitoring for bleeding risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tirofiban
What this could lead to
If it works, this could provide a new treatment option for stroke patients who don't improve enough after initial clot-busting therapy, potentially reducing long-term disability.
What could go wrong
This is a Phase 4 trial, but it's still testing a new combination approach. Tirofiban increases bleeding risk, including bleeding in the brain, which could offset any benefits. The results may not apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital,Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 101118, China

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