New biologic injection shows promise for psoriatic arthritis in phase 3 trial

NCT ID NCT04314544

Completed Disease control Sponsor: Sun Pharmaceutical Industries Limited Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tested a single injection of tildrakizumab against placebo in 508 adults with active psoriatic arthritis who had previously used anti-TNF drugs. The main goal was to see if more people achieved at least a 20% improvement in joint symptoms. The study is now complete, and results may support tildrakizumab as a treatment option for this condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tildrakizumab (a biologic drug given as a single injection)
What this could lead to: If successful, this could provide a new treatment option for people with active psoriatic arthritis who have not responded well to other therapies.
What could go wrong: This is a single-dose study, so long-term effects and durability are unknown. The trial is also limited to patients who have already tried anti-TNF drugs, so results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

psoriatic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTIVE PSORIATIC ARTHRITIS

Contacts and locations

Locations

Sun pharma site 99

Brno, 63800, Czechia
SunPharma Site No 23

Córdoba, 14004, Spain
SunPharma Site no 22

Tamarac, Florida, 33321, United States
Sunpharma Site no 26

Stafford, Texas, 77477, United States
Sunpharma Site no 27

Lincoln, Nebraska, 68516, United States
Sunpharma Site no 28

Lubbock, Texas, 79410, United States
Sunpharma Site no 29

Gilbert, Arizona, 85297, United States
Sunpharma Site no 30

Glendale, Arizona, 85306, United States
Sunpharma Site no 31

Mesa, Arizona, 85210, United States
Sunpharma Site no 33

Minot, North Dakota, 58701, United States
Sunpharma Site no 34

Greenville, South Carolina, 29601, United States
Sunpharma Site no 35

Covina, California, 91722, United States
Sunpharma Site no 37

Skokie, Illinois, 60076, United States
Sunpharma Site no 38

Schaumburg, Illinois, 60185, United States
Sunpharma Site no 41

Oak Brook, Illinois, 60523, United States
Sunpharma Site no 42

Dothan, Alabama, 36305, United States
Sunpharma Site no 44

Voorhees Township, New Jersey, 08043, United States
Sunpharma Site no 46

Gainesville, Georgia, 30501, United States
Sunpharma Site no 48

Encino, California, 91436, United States
Sunpharma Site no 49

Colleyville, Texas, 76034, United States
Sunpharma Site no 50

Austin, Texas, 78745, United States
Sunpharma Site no 52

Charlotte, North Carolina, 28204, United States
Sunpharma Site no 53

Kalispell, Montana, 59901, United States
Sunpharma Site no 54

Orland Park, Illinois, 60467, United States
Sunpharma Site no 55

Kissimmee, Florida, 34741, United States
Sunpharma Site no 56

Wilmington, North Carolina, 28401, United States
Sunpharma Site no 58

A Coruña, 15006, Spain
Sunpharma Site no 59

Valencia, 46010, Spain
Sunpharma Site no 60

Tainan, 710, Taiwan
Sunpharma Site no 62

Kaohsiung City, 833, Taiwan
Sunpharma Site no 63

Jianguo, Taichung, 402, Taiwan
Sunpharma Site no 64

Taipei, 112, Taiwan
Sunpharma Site no 65

Taipei, Pai-Tou, 112, Taiwan
Sunpharma Site no 70

Seoul, 4763, South Korea
Sunpharma Site no 71

Seoul, 3080, South Korea
Sunpharma Site no. 100

Prague, 12800, Czechia
Sunpharma Site no. 101

Prague, 14000, Czechia
Sunpharma Site no. 103

Herne, 44649, Germany
Sunpharma Site no. 104

Milan, 20089, Italy
Sunpharma Site no. 106

Ponzan, 60-529, Poland
Sunpharma Site no. 107

Lublin, 20-607, Poland
Sunpharma Site no. 108

Torun, 87-100, Poland
Sunpharma Site no. 110

Bialystok, 15-351, Poland
Sunpharma Site no. 111

Warsaw, 02-118, Poland
Sunpharma Site no. 112

Vahom, 91501, Slovakia
Sunpharma Site no. 115

Santiago de Compostela, 15706, Spain
Sunpharma Site no. 116

Málaga, 29009, Spain
Sunpharma Site no. 117

Seville, 41014, Spain
Sunpharma Site no. 121

Salt Lake City, Utah, 84132, United States
Sunpharma Site no. 122

Skokie, Illinois, 60077, United States
Sunpharma Site no. 124

Oklahoma City, Oklahoma, 73103, United States
Sunpharma Site no. 125

Sabadell, 8208, Spain
Sunpharma Site no. 127

Bangalore, Karnataka, 560079, India
Sunpharma Site no. 128

Mylapore, Chennai, 600004, India
Sunpharma Site no. 129

Lucknow, Uttar Pradesh, 226003, India
Sunpharma Site no. 130

Belagavi, Karnataka, 590016, India
Sunpharma Site no. 131

Pune, Maharashtra, 411004, India
Sunpharma Site no. 132

Hubli, Karnataka, 580021, India
Sunpharma Site no. 134

Surat, Gujarat, 395010, India
Sunpharma Site no. 136

Olsztyn, 10-117, Poland
Sunpharma Site no. 137

Wroclaw, 52-416, Poland
Sunpharma Site no. 138

Verona, 37134, Italy
Sunpharma Site no. 139

Katowice, 40-081, Poland
Sunpharma Site no. 141

Avon Park, Florida, 33825, United States
Sunpharma Site no. 142

Pune, Maharashtra, 411014, India
Sunpharma Site no. 143

Kochi, Kerala, 682040, India
Sunpharma Site no. 144

Kolkata, West Bengal, 700020, India
Sunpharma Site no. 73

Leland, North Carolina, 28451, United States
Sunpharma Site no. 74

Mesquite, Texas, 75150, United States
Sunpharma Site no. 75

Margate, Florida, 33063, United States
Sunpharma Site no. 76

Ocoee, Florida, 34761, United States
Sunpharma Site no. 78

Madrid, 28046, Spain
Sunpharma Site no. 79

Hsinchu, 300, Taiwan
Sunpharma Site no. 85

Tallinn, 10117, Estonia
Sunpharma Site no. 86

Tartu, 50708, Estonia
Sunpharma Site no. 87

Tartu, 50106, Estonia
Sunpharma Site no. 88

Martin, 3601, Slovakia
Sunpharma Site no. 91

Berlin, 12161, Germany
Sunpharma Site no. 92

Poznan, 61-113, Poland
Sunpharma Site no. 93

Bialystok, 15-879, Poland
Sunpharma Site no. 94

Krakow, 30-033, Poland
Sunpharma Site no. 95

Warsaw, Mazowiecki, 05-830, Poland
Sunpharma Site no. 96

Zlín, 760 01, Czechia
Sunpharma site 98

Trois-Rivières, Quebec, G8Z 1Y2, Canada
Sunpharma site no. 01

Tomball, Texas, 77375, United States
Sunpharma site no. 02

Hialeah, Florida, 33016, United States
Sunpharma site no. 05

New Port Richey, Florida, 34652, United States
Sunpharma site no. 07

Worcester, Massachusetts, 01605, United States
Sunpharma site no. 08

Houston, Texas, 77084, United States
Sunpharma site no. 11

Middleburg Heights, Ohio, 44130, United States
Sunpharma site no. 13

Baytown, Texas, 77521, United States
Sunpharma site no. 14

Springfield, Missouri, 65810, United States
Sunpharma site no. 15

Thousand Oaks, California, 91320, United States
Sunpharma site no. 16

San Antonio, Texas, 78229, United States
Sunpharma site no. 17

Fountain Valley, California, 92708, United States
Sunpharma site no. 20

Wichita, Kansas, 67207, United States
Sunpharma site no. 21

Clearwater, Florida, 33765, United States

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