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New drug shows promise for psoriatic arthritis in major trial

NCT ID NCT04314531

Ongoing Disease control Sponsor: Sun Pharmaceutical Industries Limited Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 study tests whether tildrakizumab, an injected drug, can reduce joint pain and swelling in people with active psoriatic arthritis who have not used anti-TNF treatments before. About 296 adults will receive either the drug or a placebo. The main goal is to see if at least 20% improvement in symptoms is achieved.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tildrakizumab

What this could lead to

If successful, tildrakizumab could offer a new treatment option for people with active psoriatic arthritis who haven't tried anti-TNF therapies.

What could go wrong

This is a late-stage trial, but results may not apply to everyone. Some participants may not respond, and side effects are possible, as with any drug.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psoriatic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTIVE PSORIATIC ARTHRITIS

Contacts and locations

Locations

  • Sunpharma Site 100

    Madrid, 28046, Spain

  • Sunpharma Site 106

    Lucknow, Uttar Pradesh, 226003, India

  • Sunpharma Site 107

    Belagavi, Karnataka, 590016, India

  • Sunpharma Site 108

    Pune, Maharashtra, 411004, India

  • Sunpharma Site 109

    Hubli, Karnataka, 580021, India

  • Sunpharma Site 110

    Bangalore, Karnataka, 560079, India

  • Sunpharma Site 111

    Surat, Gujarat, 395010, India

  • Sunpharma Site 112

    Hyderabad, Telangana, 500003, India

  • Sunpharma Site 113

    Kochi, 682040, India

  • Sunpharma Site 18

    Incheon, 22332, South Korea

  • Sunpharma Site 19

    Seoul, 4763, South Korea

  • Sunpharma Site 20

    Seoul, 3080, South Korea

  • Sunpharma Site 22

    Kitakyushu-shi, 802-8561, Japan

  • Sunpharma Site 23

    Tsu, 514-8507, Japan

  • Sunpharma Site 24

    Miyazaki, Miyazaki, 889-1692, Japan

  • Sunpharma Site 39

    Phillip, Australian Capital Territory, 2606, Australia

  • Sunpharma Site 63

    Zlín, 760 01, Czechia

  • Sunpharma Site 64

    Brno, 638 00, Czechia

  • Sunpharma Site 71

    Córdoba, 14004, Spain

  • Sunpharma Site 72

    Seville, 41013, Spain

  • Sunpharma Site 73

    Berlin, 12161, Germany

  • Sunpharma Site 74

    Poznan, 61-113, Poland

  • Sunpharma Site 75

    A Coruña, 15006, Spain

  • Sunpharma Site 84

    Nagoya, Aichi-ken, 467-0001, Japan

  • Sunpharma Site 85

    Shinjuku, Tokyo, 160-0023, Japan

  • Sunpharma Site 86

    Sendai, Miyagi, 980-8574, Japan

  • Sunpharma Site 87

    Osaka, 545-0051, Japan

  • Sunpharma Site 88

    Kumamoto, 860-8556, Japan

  • Sunpharma Site 89

    Kitakyushu, Fukuoka, 802-8561, Japan

  • Sunpharma Site 90

    tabashi City, Tokyo, 173-8606, Japan

  • Sunpharma Site 91

    Mitaka, Tokyo, 181-8611, Japan

  • Sunpharma Site 92

    Herne, 44649, Germany

  • Sunpharma Site 93

    Bialystok, 15-351, Poland

  • Sunpharma Site 94

    Lublin, 20-607, Poland

  • Sunpharma Site 95

    Bialystok, 15-879, Poland

  • Sunpharma Site 96

    Warsaw, 02-118, Poland

  • Sunpharma Site 97

    Prague, 12800, Czechia

  • Sunpharma site no. 01

    Tomball, Texas, 77375, United States

  • Sunpharma site no. 02

    New Port Richey, Florida, 34652, United States

  • Sunpharma site no. 03

    San Antonio, Texas, 78229, United States

  • Sunpharma site no. 04

    Miami Beach, Florida, 33140, United States

  • Sunpharma site no. 05

    Springfield, Missouri, 65810, United States

  • Sunpharma site no. 06

    Spokane, Washington, 99204, United States

  • Sunpharma site no. 07

    Tamarac, Florida, 33321, United States

  • Sunpharma site no. 08

    Hobart, Tasmania, 7000, Australia

  • Sunpharma site no. 09

    Lubbock, Texas, 79410, United States

  • Sunpharma site no. 10

    Lincoln, Nebraska, 68516, United States

  • Sunpharma site no. 11

    Greenville, South Carolina, 29601, United States

  • Sunpharma site no. 12

    Covina, California, 91722, United States