Can a Patient's own immune cells fight tough cancers?

NCT ID NCT05098197

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing a treatment called tumor-infiltrating lymphocytes (TILs) in 50 people with advanced liver or pancreatic cancers that have not responded to standard treatments. Doctors take immune cells from a patient's tumor, grow them in a lab, and then infuse them back into the patient after a short course of chemotherapy. The goal is to see if this approach is safe and can shrink tumors or slow cancer growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tumor-infiltrating lymphocytes (TILs)

What this could lead to

If successful, this could point toward a new treatment option for advanced liver and pancreatic cancers that have not responded to standard therapies.

What could go wrong

This is a very early (Phase 1) trial with only 50 participants, so results may not apply broadly. The treatment involves strong chemotherapy beforehand, which can cause serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma hepatobiliary neoplasm liver cancer malignant pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Tenth People's Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact