New surgery combo may save sight after eye bleed in wet AMD

NCT ID NCT04663750

First seen Feb 04, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study tests whether adding a surgical procedure to standard anti-VEGF injections can help people with wet age-related macular degeneration who have a bleed under the retina see better. About 210 adults aged 50 and older will be randomly assigned to get either injections alone or injections plus surgery. The goal is to see if the surgery leads to greater vision improvement after one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Augenzentrum am St. Franziskus-Hospital Münster

    RECRUITING

    Münster, Germany

    Contact

  • Barts Health NHST trust - Whipps Cross University Hospital

    RECRUITING

    London, E11 1NR, United Kingdom

    Contact

  • Belfast Health and Social Care Trust

    RECRUITING

    Belfast, BT9 7AB, United Kingdom

    Contact

  • Bristol Eye Hospital

    RECRUITING

    Bristol, BS1 2LX, United Kingdom

    Contact

  • Gartnavel General Hospital

    WITHDRAWN

    Glasgow, United Kingdom

  • Hull Royal Infirmary

    RECRUITING

    Hull, Yorkshire, HU3 2JZ, United Kingdom

    Contact

  • Imperial College Healthcare NHS Foundation Trust (The Western Eye Hospital)

    RECRUITING

    London, NW1 5QH, United Kingdom

    Contact

  • James Cook University Hospital, (South Tees NHSFT)

    RECRUITING

    Middlesbrough, United Kingdom

    Contact

  • Kent & Canterbury Hospital (East Kent University)

    RECRUITING

    Canterbury, Kent, CT1 3 NG, United Kingdom

    Contact

  • King's College Hospital NHS Foundation Trust

    RECRUITING

    London, London, SE5 9RS, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-••••

    Contact

  • Knappschaft Kliniken Saar GmbH, Sulzbach

    RECRUITING

    Sulzbach, Germany

    Contact

  • Leicester Royal Infirmary

    RECRUITING

    Leicester, United Kingdom

    Contact

  • Ludwig Maximilians-University München

    RECRUITING

    München, Germany

    Contact

  • Maidstone and Tunbridge Wells NHS Trust

    RECRUITING

    Maidstone, ME16 9QQ, United Kingdom

    Contact

  • Manchester Royal Eye Hospital

    RECRUITING

    Manchester, United Kingdom

    Contact

  • Mid and South Essex NHS Foundation Trust

    RECRUITING

    Chelmsford, Essex, CM1 7ET, United Kingdom

    Contact

  • Moorfields Eye Hospital

    RECRUITING

    London, EC1V 2PD, United Kingdom

    Contact

  • New Cross Hosp, Royal Wolverhampton NHST

    RECRUITING

    Wolverhampton, United Kingdom

    Contact

  • Nottingham University Hospitals

    RECRUITING

    Nottingham, United Kingdom

    Contact

  • Ophthalmology Clinic Jasne Błonia

    RECRUITING

    Lodz, Poland

    Contact

  • Oxford University Hospitals NHS Foundation Trust

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

    Contact

  • Royal Devon and Exeter Hospital

    RECRUITING

    Exeter, United Kingdom

    Contact

  • Royal Liverpool University Hospital

    RECRUITING

    Liverpool, L7 8 XP, United Kingdom

    Contact

  • Royal Victoria Infirmary

    RECRUITING

    Newcastle upon Tyne, NE1 4LP, United Kingdom

    Contact

  • Sunderland Eye Infimary

    RECRUITING

    Sunderland, Tyne and Wear, SR2 9HP, United Kingdom

    Contact

  • The Institute of Eye Surgery

    RECRUITING

    Waterford, Ireland

    Contact

  • The Princess Alexandra Eye Pavilion

    RECRUITING

    Edinburgh, Scotlan, EH3 9HA, United Kingdom

    Contact

  • Torbay and South Devon NHS

    RECRUITING

    Torquay, TQ2 7AA, United Kingdom

    Contact

  • Ulm University Hospital

    RECRUITING

    Ulm, Germany

    Contact

  • University Hospital Bern

    RECRUITING

    Bern, Switzerland

    Contact

  • University Hospital Southampton NHS foundation Trust

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

    Contact

  • University Hospitals Plymouth NHST

    RECRUITING

    Plymouth, United Kingdom

    Contact

  • University Hospitals Sussex NHS Trust

    WITHDRAWN

    Brighton, United Kingdom

  • University Medical Center Hamburg Eppendorf

    RECRUITING

    Hamburg, Germany

    Contact

  • University hospital of Würzburg

    RECRUITING

    Würzburg, Germany

    Contact

  • University of Bonn

    RECRUITING

    Bonn, Germany

    Contact

Conditions

Explore the condition pages connected to this study.