New study aims to decode cancer risk in treated thyroid nodules

NCT ID NCT05726981

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study follows 180 people who had a benign thyroid nodule treated with radiofrequency heat ablation three years ago. Researchers will use ultrasound and a fine-needle biopsy to see how the nodule looks and whether any cells have changed. The goal is to create a better way to spot cancer in these treated nodules, since current ultrasound rules don't apply well after ablation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency thermal ablation

What this could lead to

If successful, this could create a new ultrasound-based system to better predict cancer risk in treated thyroid nodules, reducing unnecessary biopsies.

What could go wrong

This is an early exploratory study with no control group, so results may not apply to all patients. The findings are descriptive and may not change current practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm nodular goiter Thyroid Nodule

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Pitié-Salpêtrière - Department of Thyroid and Endocrine Tumour Pathologies

    RECRUITING

    Paris, 75651, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••