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Can brain stimulation help stroke survivors relearn movement?

NCT ID NCT07834333

Symptom relief Sponsor: Ankara Etlik City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 22, 2026 · Last updated Sep 23, 2026 · Updated 1 time

Summary

Researchers are testing whether theta burst stimulation, a noninvasive form of brain stimulation, can improve arm and leg recovery when added to standard rehabilitation after a first ischemic stroke. The trial enrolls 60 adults aged 45 and older who are within three months of their stroke. Participants receive either active stimulation over the motor cortex, sham stimulation, or a combination, alongside at least four weeks of conventional therapy. The main measure is change in upper-extremity movement, with follow-up one month after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
theta burst stimulation, a form of noninvasive brain stimulation
What this could lead to
If it works, this could point toward a way to boost standard rehabilitation and help stroke survivors regain more arm and leg movement.
What could go wrong
The trial is small, with 60 people at one hospital, and brain stimulation has produced mixed results in stroke recovery. Benefits may be modest or fade, and the procedure can cause scalp discomfort or headaches.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of ischemic stroke due to middle cerebral artery (MCA) occlusion confirmed by magnetic resonance imaging (MRI). * Within the first 3 months after stroke. * First-ever stroke. * Age ≥45 years. * Brunnstrom stage 1, 2, or 3 for the upper extremity and hand. * No previous physical therapy after the current stroke. * Ability to maintain at least minimal semi-sitting balance. * Medically and neurologically stable. * Mini-Mental State Examination score \>24. * Native Turkish speaker who voluntarily agrees to participate and provides written informed consent. Exclusion Criteria: * History of epilepsy. * Presence of a pacemaker. * Pregnancy. * Neurological disease other than stroke. * Metallic implants in the brain or scalp, including cochlear implants. * History of brain surgery. * Comorbid disease that may significantly impair general health, such as heart f-failure or chronic obstructive pulmonary disease, and/or severe infection. * Diagnosis of malignancy. * Peripheral nerve injury and/or musculoskeletal disorder affecting motor function of the upper or lower extremities, such as fracture. * Cardiac arrhythmia. * Aphasia, spatial neglect, or visual field loss. * Visual or hearing impairment that prevents communication. * Alcohol and/or drug dependence. * Refusal to participate or failure to provide informed consent.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic stroke

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Ankara Etlik Şehir Hastanesi

    RECRUITING

    Ankara, Yenimahalle, 06170, Turkey (Türkiye)

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