Cannabis compound may calm agitation in dementia patients

NCT ID NCT05644262

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests whether a combination of two cannabis ingredients (THC and CBD) can reduce agitation in people with dementia who are eligible for hospice care. About 120 participants will receive either the study drug or a placebo for 12 weeks. The main goal is to see if agitation improves after 2 weeks of treatment.

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Contacts and locations

Locations

  • Case Western Reserve University

    Beachwood, Ohio, 44122, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Howard University

    Washington D.C., District of Columbia, 20059, United States

  • Melgar-Caro Medcenter and Community Research (MCMCR)

    Miami, Florida, 33145, United States

  • Pennington Biomedical Research Center

    Baton Rouge, Louisiana, 70808, United States

  • Ralph H. Johnson VA Medical Center

    Charleston, South Carolina, 29401, United States

  • University of Kentucky

    Lexington, Kentucky, 40504, United States

  • University of Maryland

    Baltimore, Maryland, 21201, United States

  • University of South Florida

    Tampa, Florida, 33612, United States

  • Vanderbilt University Medical Center Center for Cognitive Medicine

    Nashville, Tennessee, 37212, United States

Conditions

Explore the condition pages connected to this study.