New asthma drug tezspire put to the test in Long-Term safety study

NCT ID NCT05729711

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks 416 people with severe asthma that isn't controlled by standard treatments. All participants receive Tezspire injections and are monitored for side effects, including serious allergic reactions, infections, and heart problems. The goal is to see how safe and effective the drug is over long-term use in real-world conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tezspire (tezepelumab) injection
What this could lead to: If successful, this study could confirm that Tezspire is safe and effective for long-term use in people with severe asthma that other treatments can't control.
What could go wrong: This is an observational follow-up study, not a new treatment trial. It may reveal unexpected side effects or show that the drug works less well over time. Results may not apply to all asthma patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIAL ASTHMA (ONLY THE PATIENTS WITH SEVERE OR INTRACTABLE BRONCHIAL ASTHMA WHICH COULD NOT BE CONTROLLED WITH THE EXISTING THERAPY)

Contacts and locations

Locations

Research Site

Aichi, Japan
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Akita, Japan
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Aomori, Japan
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Chiba, Japan
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Fukui, Japan
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Fukuoka, Japan
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Gifu, Japan
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Gunma, Japan
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Hiroshima, Japan
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Hokkaido, Japan
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Hyōgo, Japan
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Ibaraki, Japan
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Ishikawa, Japan
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Kagawa, Japan
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Kanagawa, Japan
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Kumamoto, Japan
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Kyoto, Japan
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Mie, Japan
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Miyagi, Japan
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Nara, Japan
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Numakunai, Japan
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Okayama, Japan
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Osaka, Japan
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Ōita, Japan
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Saitama, Japan
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Shimane, Japan
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Shizuoka, Japan
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Tochigi, Japan
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Tokyo, Japan
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Wakayama, Japan
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Yamagata, Japan
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Yamaguchi, Japan
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Yamanashi, Japan