New tetanus antibody could replace Blood-Derived treatments

NCT ID NCT06939777

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 1/2 trial tested a new lab-made antibody called SNA02-48 for treating tetanus in 255 Chinese adults. The study compared SNA02-48 to the standard treatment (human tetanus immunoglobulin) to see if it is safe and how well it works. The goal is to find a more reliable and potentially safer option for preventing tetanus infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SNA02-48 (a lab-made antibody against tetanus toxin)

What this could lead to

If successful, this could offer a new, safer alternative to current tetanus treatments derived from human blood.

What could go wrong

This is an early-phase trial (Phase 1/2) with only 255 participants, so results may not confirm effectiveness or safety in larger populations. The antibody may not work as well as existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tetanus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Second Hospital of Anhui Medical Universiy

    Hefei, Anhui, 230601, China