Could a testosterone boost help fight resistant prostate cancer?

NCT ID NCT04363164

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study is for men with a type of advanced prostate cancer that no longer responds to standard hormone therapy. It compares two treatments: taking the drug enzalutamide alone versus taking it along with high-dose testosterone in cycles. The goal is to see if the combination can delay cancer growth better than enzalutamide alone. About 150 men will participate, and the study is currently recruiting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CASTRATION RESISTANT METASTATIC PROSTATE CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Dana-Faber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • University of California, San Diego (UCSD)

    RECRUITING

    San Diego, California, 92037, United States

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

  • University of Washington/Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.