Could a testosterone boost improve prostate cancer treatment?

NCT ID NCT04363164

First seen Apr 08, 2026 · Last updated May 12, 2026 · Updated 3 times

Summary

This study tests whether giving high-dose testosterone followed by the drug enzalutamide works better than enzalutamide alone for men with a type of advanced prostate cancer that no longer responds to standard hormone therapy. About 150 men without pain from their cancer will take part. The goal is to see if the sequence delays cancer growth or spread.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Faber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California, San Diego (UCSD)

    RECRUITING

    San Diego, California, 92037, United States

    Contact Email: •••••@•••••

    Contact

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact

    Contact Email: •••••@•••••

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

    Contact Email: •••••@•••••

    Contact

  • University of Washington/Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.