Tailored chemo dosing shows promise for adult leukemia patients
NCT ID NCT00136435
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 21 times
Summary
This study tested a personalized dosing approach for the chemotherapy drug L-asparaginase in 100 adults aged 18-50 with untreated acute lymphoblastic leukemia (ALL). The goal was to find a safe and effective dose by adjusting it based on each patient's drug levels. The study measured how many patients could complete all 30 planned doses and tracked disease-free survival over 4 years.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Hospital Maisonneuve-Rosemont
Montreal, Quebec, Canada
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London Health Sciences Centre
London, Ontario, Canada
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Manitoba Blood & Marrow Transplant Program CancerCare Manitoba
Winnipeg, Manitoba, Canada
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Massachusetts General Hospital
Boston, Massachusetts, 02115, United States
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McMaster University Medical Center
Hamilton, Ontario, Canada
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Queen Elizabeth II
Halifax, Canada
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Queen's University
Kingston, Ontario, Canada
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Royal Victoria Hospital
Montreal, Quebec, Canada
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Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada
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Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
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University Of Columbia Medical Center
New York, New York, United States
Conditions
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