Could an MS drug tame a rare Virus-Caused paralysis?

NCT ID NCT04799288

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether teriflunomide, a drug already used for multiple sclerosis, can help people with a rare spinal cord disease called HAM/TSP caused by the HTLV-1 virus. About 24 adults will take the drug daily for 9 months to see if it reduces harmful immune activity and improves symptoms. The goal is to find a safe treatment for this progressive condition that currently has no approved therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States