New radiation therapy shows promise for Hard-to-Treat gut cancers

NCT ID NCT07404176

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a new radioactive drug called Terbium-161 DOTATATE in 20 people with advanced neuroendocrine tumors that have spread and stopped responding to standard treatment. The drug delivers radiation directly to cancer cells, aiming to control the disease with fewer side effects. Researchers will measure how well it shrinks or stabilizes tumors and monitor safety through blood tests and scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Terbium-161 DOTATATE (a radioactive drug that targets cancer cells)

What this could lead to

If successful, this could offer a new treatment option for patients with neuroendocrine tumors that no longer respond to current therapies, potentially with fewer side effects.

What could go wrong

This is a small, early-phase trial with only 20 participants, so results may not apply to everyone. The drug is experimental, and its safety and effectiveness are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

digestive system neuroendocrine tumor, grade 1/2 neoplasm neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)

    RECRUITING

    Navi Mumbai, Maharashtra, 410210, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tata Memorial Hospital, Mumbai, India

    RECRUITING

    Mumbai, Maharashtra, 400012, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••