New drug trial aims to preserve insulin production in youth with type 1 diabetes

NCT ID NCT07088068

Recruiting now Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether an intravenous drug called teplizumab can help young people (ages 1-25) who were recently diagnosed with type 1 diabetes. The goal is to see if the drug can help the body preserve its own ability to make some insulin, potentially reducing the need for mealtime insulin injections and improving overall blood sugar control. Participants will receive either the study drug or a placebo infusion while continuing their standard insulin therapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AM Diabetes & Endocrinology Center- Site Number : 8400004
RECRUITING

Bartlett, Tennessee, 38133, United States
AOU Maggiore della Carità - Site Number : 3800015
RECRUITING

Novara, 28100, Italy

Contact Email: •••••@•••••
Asheville Clinical Research- Site Number : 8400045
RECRUITING

Asheville, North Carolina, 28803, United States

Contact Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Atlanta Diabetes Associates- Site Number : 8400036
RECRUITING

Atlanta, Georgia, 30318, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Azienda Ospedaliera Universitaria Meyer IRCCS - Site Number : 3800001
RECRUITING

Florence, Firenze, 50139, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Barbara Davis Center for Childhood Diabetes- Site Number : 8400031
RECRUITING

Aurora, Colorado, 80045, United States
Benaroya Research Institute at Virginia Mason- Site Number : 8400038
RECRUITING

Seattle, Washington, 98101, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Centro de Diabetes Curitiba- Site Number : 0760006
RECRUITING

Curitiba, Paraná, 80810-040, Brazil
Centro de Pesquisa Clínica de Marília - CPCLIM- Site Number : 0760002
RECRUITING

Marília, São Paulo, 17504-072, Brazil
Centro de Pesquisas Clínicas - São Paulo- Site Number : 0760011
RECRUITING

São Paulo, 01228-200, Brazil
Children's Mercy Adelle Hall Campus- Site Number : 8400010
RECRUITING

Kansas City, Missouri, 64108, United States
Columbia University Irving Medical Center- Site Number : 8400009
RECRUITING

New York, New York, 10032, United States
Encore Medical Research - Hollywood- Site Number : 8400061
RECRUITING

Hollywood, Florida, 33024, United States
Endocrine Associates of West Village- Site Number : 8400064
RECRUITING

New York, New York, 10001, United States
Hospital Israelita Albert Einstein- Site Number : 0760001
RECRUITING

São Paulo, 05651-901, Brazil
Hospital Universitario Clementino Fraga Filho- Site Number : 0760008
RECRUITING

Rio de Janeiro, 21941-913, Brazil
Hospital Universitario Walter Cantidio- Site Number : 0760009
RECRUITING

Fortaleza, Ceará, 60430-270, Brazil
IACT Health - Columbus - Talbotton Road- Site Number : 8400003
RECRUITING

Columbus, Georgia, 31904, United States
IRCCS Istituto Giannina Gaslini - Site Number : 3800008
RECRUITING

Genoa, Genova, 16147, Italy

Contact Phone: •••-•••-••••
Institute of Endocrinology Diabetes, Health & Hormones- Site Number : 8400050
RECRUITING

Stockbridge, Georgia, 30281, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Investigational Site Number : 0320005
RECRUITING

Buenos Aires, 1419, Argentina
Investigational Site Number : 0560001
RECRUITING

Leuven, 3000, Belgium
Investigational Site Number : 0560002
RECRUITING

Jette, 1090, Belgium
Investigational Site Number : 0560004
RECRUITING

Namur, 5000, Belgium
Investigational Site Number : 0560005
RECRUITING

Brussels, 1020, Belgium
Investigational Site Number : 0560006
RECRUITING

Liège, 4000, Belgium
Investigational Site Number : 0560007
RECRUITING

Edegem, 2650, Belgium
Investigational Site Number : 0560008
RECRUITING

Leuven, 3000, Belgium
Investigational Site Number : 0560009
RECRUITING

Brussels, 1070, Belgium
Investigational Site Number : 1240002
RECRUITING

Halifax, Nova Scotia, B3H 2Y9, Canada
Investigational Site Number : 1560001
RECRUITING

Changsha, 410011, China
Investigational Site Number : 1560002
RECRUITING

Wuhan, 430030, China
Investigational Site Number : 1560003
RECRUITING

Beijing, 100034, China
Investigational Site Number : 1560005
RECRUITING

Nanjing, 210008, China
Investigational Site Number : 1560007
RECRUITING

Guangzhou, 510120, China
Investigational Site Number : 1560009
RECRUITING

Changchun, 130041, China
Investigational Site Number : 1560010
RECRUITING

Harbin, 150001, China
Investigational Site Number : 1560012
RECRUITING

Hangzhou, 310014, China
Investigational Site Number : 1560013
RECRUITING

Shenyang, 110004, China
Investigational Site Number : 1560014
RECRUITING

Hangzhou, 310009, China
Investigational Site Number : 1560016
RECRUITING

Luoyang, New Jersey, 471003, China
Investigational Site Number : 1560018
RECRUITING

Nanchang, 330006, China
Investigational Site Number : 1560019
RECRUITING

Tianjin, 300052, China
Investigational Site Number : 1560026
RECRUITING

Hohhot, 010050, China
Investigational Site Number : 1560027
RECRUITING

Zhenjiang, 212000, China
Investigational Site Number : 1560031
RECRUITING

Shanghai, 200032, China
Investigational Site Number : 1560033
RECRUITING

Beijing, 100045, China
Investigational Site Number : 1560037
RECRUITING

Guangzhou, 510620, China
Investigational Site Number : 1560039
RECRUITING

Wuhan, 430010, China
Investigational Site Number : 1560040
RECRUITING

Hangzhou, 310003, China
Investigational Site Number : 1560041
RECRUITING

Wuxi, 214023, China
Investigational Site Number : 1560042
RECRUITING

Chengdu, 610091, China
Investigational Site Number : 1560043
RECRUITING

Nanchang, 330038, China
Investigational Site Number : 1560045
RECRUITING

Shenzhen, 518026, China
Investigational Site Number : 1560050
RECRUITING

Pingxiang, Colorado, 337055, China
Investigational Site Number : 1560054
RECRUITING

Nanjing, 210029, China
Investigational Site Number : 1560055
RECRUITING

Chengdu, 610072, China
Investigational Site Number : 1560059
RECRUITING

Jinan, 250001, China
Investigational Site Number : 1560060
RECRUITING

Yueyang, 414000, China
Investigational Site Number : 2030001
RECRUITING

Prague, 150 06, Czechia
Investigational Site Number : 2030003
RECRUITING

Prague, 140 21, Czechia
Investigational Site Number : 2030004
RECRUITING

Prague, 128 08, Czechia
Investigational Site Number : 2500002
RECRUITING

Paris, 75010, France
Investigational Site Number : 2500005
RECRUITING

Pau, 64000, France
Investigational Site Number : 2500007
RECRUITING

Strasbourg, 67000, France
Investigational Site Number : 2500008
RECRUITING

Paris, 75651, France
Investigational Site Number : 2500009
RECRUITING

Paris, 75019, France
Investigational Site Number : 2760001
RECRUITING

Ulm, 89081, Germany
Investigational Site Number : 2760002
RECRUITING

Augsburg, 86156, Germany
Investigational Site Number : 2760005
RECRUITING

Hanover, 30173, Germany
Investigational Site Number : 2760008
RECRUITING

Bielefeld, 33617, Germany
Investigational Site Number : 2760010
RECRUITING

Munich, 81675, Germany
Investigational Site Number : 3760001
RECRUITING

Ramat Gan, 5262100, Israel
Investigational Site Number : 3760002
RECRUITING

Petah Tikva, 4920235, Israel
Investigational Site Number : 3760003
RECRUITING

Petah Tikva, 4941492, Israel
Investigational Site Number : 3760004
RECRUITING

Tel Aviv, 6423906, Israel
Investigational Site Number : 3760005
RECRUITING

Jerusalem, 9112001, Israel
Investigational Site Number : 3760006
RECRUITING

Rehovot, 7610001, Israel
Investigational Site Number : 3800002
RECRUITING

Verona, 37126, Italy
Investigational Site Number : 3800005
RECRUITING

Milan, Milano, 20154, Italy
Investigational Site Number : 3800010
RECRUITING

Turin, Torino, 10126, Italy
Investigational Site Number : 3800011
RECRUITING

Milan, Milano, 20157, Italy
Investigational Site Number : 3800012
RECRUITING

Rome, Roma, 00161, Italy
Investigational Site Number : 5280001
RECRUITING

Rotterdam, 3011 TA, Netherlands
Investigational Site Number : 5280002
RECRUITING

Leiden, 2333 ZA, Netherlands
Investigational Site Number : 6160001
RECRUITING

Warsaw, Masovian Voivodeship, 02-117, Poland
Investigational Site Number : 6160005
RECRUITING

Lodz, Lódzkie, 92-213, Poland
Investigational Site Number : 7240001
RECRUITING

Seville, Sevilla, 41013, Spain
Investigational Site Number : 7240003
RECRUITING

Sabadell, Barcelona [Barcelona], 08208, Spain
Investigational Site Number : 7240007
RECRUITING

Madrid, 28046, Spain
Investigational Site Number : 7240009
RECRUITING

Madrid, 28034, Spain
Investigational Site Number : 7240011
RECRUITING

Madrid, 28040, Spain
Investigational Site Number : 7240012
RECRUITING

Santiago de Compostela, A Coruña [La Coruña], 15706, Spain
Investigational Site Number : 7240014
RECRUITING

Pontevedra, Pontevedra [Pontevedra], 36312, Spain
Investigational Site Number : 7240015
RECRUITING

Palma, 07120, Spain
Investigational Site Number : 7240016
RECRUITING

Pamplona, Navarre, 31008, Spain
Investigational Site Number : 7240017
RECRUITING

Barcelona, Barcelona [Barcelona], 08035, Spain
Investigational Site Number : 7240019
RECRUITING

San Cristóbal de La Laguna, Santa Cruz De Tenerife, 38320, Spain
Investigational Site Number : 7240020
RECRUITING

Barakaldo, Basque Country, 48903, Spain
Investigational Site Number : 7240021
RECRUITING

Seville, Sevilla, 41009, Spain
Investigational Site Number : 7240022
RECRUITING

Málaga, 29010, Spain
Investigational Site Number : 7240023
RECRUITING

Alcalá de Henares, Madrid, 28805, Spain
Investigational Site Number : 8260001
RECRUITING

Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom
Investigational Site Number : 8260002
RECRUITING

Glasgow, Glasgow City, G51 4TF, United Kingdom
Investigational Site Number : 8260004
RECRUITING

Dundee, Dundee City, DD1 9SY, United Kingdom
Investigational Site Number : 8260005
RECRUITING

Leeds, LS9 7TF, United Kingdom
Investigational Site Number : 8260006
RECRUITING

Guildford, Surrey, GU2 7XX, United Kingdom
Investigational Site Number : 8260007
RECRUITING

London, London, City of, SE5 9RL, United Kingdom
Investigational Site Number : 8260009
RECRUITING

London, England, E1 1BB, United Kingdom
Investigational Site Number : 8260010
RECRUITING

Reading, RG1 5AN, United Kingdom
Investigational Site Number : 8260011
RECRUITING

Bath, Somerset, BA1 3NG, United Kingdom
Investigational Site Number : 8260012
RECRUITING

London, England, SW10 9NH, United Kingdom
Marvel Clinical Research- Site Number : 8400042
RECRUITING

Huntington Beach, California, 92647, United States
Mary Bridge Children's Outpatient Center- Site Number : 8400037
RECRUITING

Tacoma, Washington, 98405, United States
Mayo Clinic in Rochester - Minnesota- Site Number : 8400019
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Rocky Mountain Clinical Research - Idaho Falls- Site Number : 8400001
RECRUITING

Idaho Falls, Idaho, 83404, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Scottsdale Clinical Trials- Site Number : 8400044
RECRUITING

Scottsdale, Arizona, 85260, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
St. Luke's Children's Hospital- Site Number : 8400014
RECRUITING

Boise, Idaho, 83712, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Children's Hospital of Philadelphia- Site Number : 8400039
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University at Buffalo - Jacobs School of Medicine- Site Number : 8400006
RECRUITING

Buffalo, New York, 14203, United States
University of California San Francisco - Mission Bay- Site Number : 8400011
RECRUITING

San Francisco, California, 94158, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Florida College of Medicine- Site Number : 8400054
RECRUITING

Gainesville, Florida, 32610, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Email: •••••@•••••
University of South Florida- Site Number : 8400013
RECRUITING

Tampa, Florida, 33612, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Yale University School of Medicine- Site Number : 8400005
RECRUITING

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

TYPE 1 DIABETES MELLITUS