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Tennis elbow study probes the Brain's natural painkiller

NCT ID NCT07178288

Knowledge-focused Sponsor: The Hashemite University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study at Hashemite University looks at how people with and without tennis elbow feel pressure pain and how their bodies briefly turn down pain after a cold stimulus. Participants answer short questionnaires and have their pressure-pain threshold tested with a handheld device. To test the body's built-in anti-pain system, one hand is placed in ice water and pain sensitivity is measured before, during, and after. The findings may help improve future assessment and treatment of musculoskeletal pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 38 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

TE Group Inclusion Criteria: Patients with Tennis Elbow confirmed at initial assessment by the Primary Investigator (PI) Unilateral elbow pain \> 6 weeks duration reproduced on at least two of the following tests: * Palpation of the lateral epicondyle * Isometric testing of the wrist extensors * Middle finger extension test * Passive stretch of wrist extensors * Resisted hand gripping using a dynamometer * Upper limb neurodynamic test-radial nerve bias (ULNDT-RN) Exclusion Criteria: * History of chronic pain conditions (e.g. fibromyalgia, irritable bowel * syndrome, temporomandibular dysfunction, migraines) * Neurological or sensory dysfunction (especially in the upper limbs) * History of chronic musculoskeletal pain (e.g. arthritis, chronic low back * pain) * Contraindications to cold application (i.e. Reynaud's disease, diabetes) * Current or long-term use of pain medication or anti-depressants Healthy Group The asymptomatic group included adults (18-65 years) without pain (acute or chronic) at least 3 months before the experimental sessions.

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Conditions

The condition(s) this trial relates to.

Ceroid lipofuscinosis, neuronal 1, infantile epicondylitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Conditioned pain modulation (CPM) Health adult subjects Lateral elbow tendinopathy (tennis elbow) Pressure pain threshold (PPT) Tennis elbow

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Hashemite University, Department of Physical Therapy; Community Rehabilitation Center Clinics

    RECRUITING

    Zarqa, Zarqa Governorate, 13115, Jordan

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