Can a Clot-Buster help stroke patients on blood thinners?
NCT ID NCT07092709
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called tenecteplase in people who have had a stroke and recently took a blood thinner (DOAC). The goal is to see if the drug helps them recover better after 90 days. About 912 participants will receive either tenecteplase or a placebo within 24 hours of their stroke.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tenecteplase (a clot-busting drug)
- What this could lead to
- If it works, this could provide a safe way to treat stroke in patients who have recently taken blood thinners, potentially improving their recovery.
- What could go wrong
- This is a Phase 3 trial, but it's still uncertain whether tenecteplase will be safe or effective in this specific group. There is a risk of bleeding, especially since patients are on blood thinners.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
RECRUITINGGuangzhou, Guangdong, 510000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could vague stroke symptoms delay lifesaving treatment?