Could zapping the brain improve depression and memory?

NCT ID NCT07191392

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether temporal interference stimulation (TIS), a non-invasive brain stimulation technique, can improve memory and mood in people with depression. Sixty adults with depression will receive either real or sham TIS over 30 minutes. Researchers will measure changes in memory tasks and depression scores to see if TIS helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Temporal Interference Stimulation (TIS) device

What this could lead to

If it works, this could point toward a non-invasive brain stimulation method to ease depression symptoms and improve memory.

What could go wrong

This is a small, early-stage trial with 60 participants, so results may not apply widely. The sham control mimics sensation, but real effects may be subtle or absent.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anhui Medical University

    RECRUITING

    Hefei, Anhui, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Anhui Mental Health Center

    RECRUITING

    Hefei, Anhui, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••