Could zapping the brain improve depression and memory?

NCT ID NCT07191392

Recruiting now Symptom relief Sponsor: The Second Hospital of Anhui Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether temporal interference stimulation (TIS), a non-invasive brain stimulation technique, can improve memory and mood in people with depression. Sixty adults with depression will receive either real or sham TIS over 30 minutes. Researchers will measure changes in memory tasks and depression scores to see if TIS helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Temporal Interference Stimulation (TIS) device
What this could lead to: If it works, this could point toward a non-invasive brain stimulation method to ease depression symptoms and improve memory.
What could go wrong: This is a small, early-stage trial with 60 participants, so results may not apply widely. The sham control mimics sensation, but real effects may be subtle or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE DISORDER TEMPORAL INTERFERENCE STIMULATION

Contacts and locations

Locations

Anhui Medical University
RECRUITING

Hefei, Anhui, China
Anhui Mental Health Center
RECRUITING

Hefei, Anhui, China

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