New pain drug may get your gut moving faster after surgery
NCT ID NCT07412223
First seen Feb 23, 2026 · Last updated Jun 23, 2026 · Updated 18 times
Summary
This study tests whether tegileridine, a new painkiller, helps the bowel recover faster after abdominal surgery compared to morphine. About 152 adults having elective abdominal surgery will use a patient-controlled pain pump with either tegileridine or morphine for up to 72 hours. Researchers will measure how quickly participants can eat solid food and pass gas or have a bowel movement, along with pain levels and side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tegileridine (with dexmedetomidine)
What this could lead to
If it works, this could offer a pain relief option after abdominal surgery that helps the gut recover faster than standard morphine.
What could go wrong
This is a Phase 4 trial, but it's small (152 people) and hasn't started yet. Results may not apply to all surgeries or patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.