New drug shows promise against rare eye cancer before liver surgery

NCT ID NCT07057596

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing a drug called tebentafusp in 19 people with a rare eye cancer (uveal melanoma) that has spread to the liver. Participants receive weekly infusions for 6 months, then may have surgery to remove any remaining tumors. The goal is to see if the drug can completely eliminate cancer cells before surgery and help keep the cancer from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tebentafusp (a drug given intravenously)

What this could lead to

If successful, this could offer a new treatment option that shrinks liver tumors before surgery, potentially delaying or preventing the cancer from coming back.

What could go wrong

This is a small, early-phase trial with only 19 participants, so results may not apply to everyone. Tebentafusp can cause serious side effects, and it is not yet known if it will work better than current treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

melanoma metastatic melanoma Neoplasm Metastasis uveal melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Charité - Universitätsmedizin Berlin

    RECRUITING

    Berlin, State of Berlin, 10117, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Consorcio Hospital General Universitario de Valencia

    RECRUITING

    Valencia, Valencia, 46014, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital La Paz

    RECRUITING

    Madrid, Madrid, 28046, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Catala d'Oncologia (ICO) Hospitalet

    NOT_YET_RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••