New hope for Tough-to-Treat melanoma: experimental drug trial seeks to extend lives

NCT ID NCT05549297

Recruiting now Disease control Sponsor: Immunocore Ltd Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug called tebentafusp, given alone or with pembrolizumab, works better than standard care options for people with advanced melanoma that has worsened despite previous treatments. The trial will enroll 540 participants with specific genetic markers to see if these approaches help people live longer. Researchers will compare survival rates and monitor side effects to determine the safest, most effective treatment approach.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

A.O.U Senese Policlinico Santa Maria alle Scotte
RECRUITING

Siena, 53100, Italy
AKH - Medizinische Universität Wien
RECRUITING

Vienna, 1090, Austria
Addenbrooke's Hospital
RECRUITING

Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
Alfred Health
RECRUITING

Melbourne, Victoria, 3004, Australia
Azienda Ospedaliera di Perugia Ospedale S. Maria della Misericordia
RECRUITING

Perugia, 6156, Italy
BC Cancer
RECRUITING

Vancouver, British Columbia, V5Z 4E6, Canada
Beth Israel Deaconess Medical Center (BIDMC)
RECRUITING

Boston, Massachusetts, 02215, United States
CHU de Bordeaux - Hopital Saint Andre
RECRUITING

Bordeaux, 22075, France
Centre Leon Berard
RECRUITING

Lyon, Cedex, 69373, France
Centrum Onkologii im. prof. F. Lukaszczyka w Bydgoszczy
RECRUITING

Bydgoszcz, 85-796, Poland
Charité - Campus Charité Mitte
RECRUITING

Berlin, 10115, Germany
Cliniques Universitaires Sain-Luc
RECRUITING

Brussels, 1200, Belgium
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Roma, 00168, Italy
Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Gallipoli Medical Research Foundation (GMRF)
RECRUITING

Greenslopes, Queensland, 4120, Australia
Gibbs Cancer Center and Research Institute
RECRUITING

Spartanburg, South Carolina, 29303, United States
Guys & St Thomas' NHS Foundation Trust
RECRUITING

London, SE1 9RT, United Kingdom
Hopital Saint Lous - APHP
RECRUITING

Paris, 75010, France
Hopital de la Timone [Recruiting]
RECRUITING

Marseille, 13005, France
Hospital Clinico de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital General Universitario Gregorio Marañon
RECRUITING

Madrid, 28007, Spain
Hospital General Universitario de Valencia
RECRUITING

Valencia, 46014, Spain
Hospital Regional Universitario de Malaga
RECRUITING

Málaga, 29010, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Houston Methodist Hospital/Houston Methodist Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Institut Gustave Roussy
RECRUITING

Villejuif, Cedex, 94805, France
Institute Claudius Regaud
RECRUITING

Toulouse, Cedex, 31059, France
Instituto Nazionale Tumori Fondazione G. Pascale
RECRUITING

Napoli, 80131, Italy
Johannes Wesling Klinikum Minden
RECRUITING

Minden, 32429, Germany
Kantonsspital St. Gallen
RECRUITING

Sankt Gallen, 9000, Switzerland
Kepler Universitätsklinikum
RECRUITING

Linz, 4020, Austria
LKH - Universitaetsklinikum Graz
RECRUITING

Graz, 8036, Austria
LMU-Campus Innenstadt
RECRUITING

München, 80337, Germany
Lady Davis Institute for Medical Research (LDI) Jewish General Hospital (JGH)
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Leeds General Infirmary
RECRUITING

Leeds, LS1 3EX, United Kingdom
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic Arizona
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic Minnesota
RECRUITING

Rochester, Minnesota, 55905, United States
Melanoma Institute Australia
RECRUITING

Wollstonecraft, New South Wales, 2065, Australia
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10068, United States
Mount Vernon Cancer Center
RECRUITING

Middlesex, HA6 2RN, United Kingdom
Narodowy Instytut Onkologii-im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy
RECRUITING

Warsaw, 02781, Poland
Northwell Health Cancer Institute - Zuckerberg Cancer Center
RECRUITING

Lake Success, New York, 11042, United States
OU Health Stephenson Cancer Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Orlando Health Cancer Institute
RECRUITING

Orlando, Florida, 32806, United States
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia
Princess Margaret Hospital
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Queen Elizabeth Hospital
RECRUITING

Birmingham, West Midlands, B15 2TH, United Kingdom
Royal Marsden Hospital - Chelsea
RECRUITING

London, SW3 6JJ, United Kingdom
Royal Marsden Hospital - Sutton
RECRUITING

Sutton, SM2 5PT, United Kingdom
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08901, United States
Sarah Cannon Research Institute UK
RECRUITING

London, SE1 9RT, United Kingdom
St Elizabeth Healthcare (St Elizabeth Medical
RECRUITING

Edgewood, Kentucky, 41017, United States
St Elizabeth Healthcare (St Elizabeth Medical Center)
RECRUITING

Edgewood, Kentucky, 41017, United States
Szpital Kliniczny im.Heliodora Swiecickiego Uniwersytetu Medycznego im.K. Marcinkowskiego w Poznaniu
RECRUITING

Poznan, 60355, Poland
The Christie NHS Foundation Trust
RECRUITING

Manchester, England, M20 4BX, United Kingdom
The Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States
Thomas Jefferson University Medical Oncology Clinic
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UPMC Hillman Cancer Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
UZ Brussel
RECRUITING

Jette, 1090, Belgium
UZ Leuven
RECRUITING

Leuven, 3000, Belgium
Universitaetsklinikum Erlangen
RECRUITING

Erlangen, 91054, Germany
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Hamburg-Eppendorf
RECRUITING

Hamburg, 20246, Germany
Universitaetsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
Universitaetsklinikum Schleswig-Holstein
RECRUITING

Schleswig, Kiel, 24105, Germany
Universitaetsklinikum Schleswig-Holstein
RECRUITING

Kiel, 24105, Germany
Universitaetsklinikum Tübingen
RECRUITING

Tübingen, 72076, Germany
Universitaetsspital Zurich
RECRUITING

Zurich, 8058, Switzerland
Universitatsklinik fur Innere Medizin 3
RECRUITING

Salzburg, 5020, Austria
Universitatsklinikum Carl Gustav Carus Dresden
RECRUITING

Dresden, 01307, Germany
University of Kansas Cancer Center - Westwood
RECRUITING

Westwood, Kansas, 66205, United States
University of Minnesota Medical Center
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Tennessee Medical Center
RECRUITING

Knoxville, Tennessee, 37920, United States
University of Utah Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 84112, United States
Uniwersyteckie Centrum Kliniczne (UCK) - Klinika Onkologii i Radioterapii
RECRUITING

Gdansk, 80214, Poland
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Winship Cancer Institute of Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED MELANOMA